TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha1beta3 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2(Rat)
Roche Pharma Research and Early Development
Curated by ChEMBL
Roche Pharma Research and Early Development
Curated by ChEMBL
Affinity DataEC50: >2.40E+4nMAssay Description:Displacement of [3H]-flumazenil from rat GABA-A receptor alpha5beta3gamma2 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataEC50: 2.44E+3nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha6beta3 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataEC50: 970nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha4beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of C57BL/6 mouse GABAA receptor alpha1beta3gamma2 assessed as increase in GABA-induced current response at -60 mV hold...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataEC50: 60nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha4beta3 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Rat)
Roche Pharma Research and Early Development
Curated by ChEMBL
Roche Pharma Research and Early Development
Curated by ChEMBL
Affinity DataEC50: >2.40E+4nMAssay Description:Displacement of [3H]-flumazenil from rat GABA-A receptor alpha3beta3gamma2 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-3/gamma-2(Rat)
Roche Pharma Research and Early Development
Curated by ChEMBL
Roche Pharma Research and Early Development
Curated by ChEMBL
Affinity DataEC50: >2.40E+4nMAssay Description:Displacement of [3H]-flumazenil from rat GABA-A receptor alpha2beta3gamma2 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataEC50: 860nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha1beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataEC50: 2.01E+3nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha1beta3gamma2 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha1beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataEC50: 150nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha4beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataEC50: 170nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha6beta3 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataEC50: 870nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha6beta3gamma2 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3delta expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3delta expressed in HEK293 cell membranes after 90 mins in presence of GABA by liquid sci...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3delta expressed in HEK293 cell membranes after 90 mins in presence of GABA by liquid sci...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha4beta3delta expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 760nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3delta expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 860nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3delta expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 870nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3delta expressed in HEK293 cell membranes after 90 mins in presence of GABA by liquid sci...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 930nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3gamma2 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3 expressed in HEK293 cell membranes after 90 mins in presence of GABA by liquid scintill...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3delta expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 1.09E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3gamma2 expressed in HEK293 cell membranes after 90 mins in presence of GABA by liquid sc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3delta expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 1.28E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3gamma2 expressed in HEK293 cell membranes after 90 mins in presence of GABA by liquid sc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 1.29E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3 expressed in HEK293 cell membranes after 90 mins in presence of GABA by liquid scintill...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 1.86E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha4beta3 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 2.18E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3delta expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 3.06E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 3.29E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha4beta3gamma2 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 3.39E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3gamma2 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 4.07E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3 expressed in HEK293 cell membranes after 90 mins in presence of GABA by liquid scintill...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 4.34E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3gamma2 expressed in HEK293 cell membranes after 90 mins in presence of GABA by liquid sc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 5.51E+3nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3gamma2 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/delta(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 1.01E+4nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3delta expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz
Curated by ChEMBL
Johannes Gutenberg University Mainz
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Displacement of [3H]EBOB from rat GABA-A receptor alpha6beta3gamma2 expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of C57BL/6 mouse GABAA receptor alpha1beta3gamma2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2(Rat)
Roche Pharma Research and Early Development
Curated by ChEMBL
Roche Pharma Research and Early Development
Curated by ChEMBL
Affinity DataKi: 7.57nMAssay Description:Displacement of [3H]flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha-5-beta-3-gamma-2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2(Rat)
Roche Pharma Research and Early Development
Curated by ChEMBL
Roche Pharma Research and Early Development
Curated by ChEMBL
Affinity DataKi: 10.3nMAssay Description:Displacement of [3H]flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha-5-beta-3-gamma-2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2(Rat)
Roche Pharma Research and Early Development
Curated by ChEMBL
Roche Pharma Research and Early Development
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Binding affinity for recombinant rat GABA-A receptor alpha-5-beta-3-gamma-2 subunits expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2(Rat)
Roche Pharma Research and Early Development
Curated by ChEMBL
Roche Pharma Research and Early Development
Curated by ChEMBL
Affinity DataKi: 17.2nMAssay Description:Displacement of [3H]flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha-5-beta-3-gamma-2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2(Rat)
Roche Pharma Research and Early Development
Curated by ChEMBL
Roche Pharma Research and Early Development
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Binding affinity for recombinant rat GABA-A receptor alpha-5-beta-3-gamma-2 subunits expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2(Rat)
Roche Pharma Research and Early Development
Curated by ChEMBL
Roche Pharma Research and Early Development
Curated by ChEMBL
Affinity DataKi: 24.1nMAssay Description:Displacement of [3H]flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha-5-beta-3-gamma-2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2(Rat)
Roche Pharma Research and Early Development
Curated by ChEMBL
Roche Pharma Research and Early Development
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Inhibition of [3H]flumazenil binding to rat alpha-5-beta-3-gamma-2 GABA-A receptor subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-3/gamma-2(Rat)
Roche Pharma Research and Early Development
Curated by ChEMBL
Roche Pharma Research and Early Development
Curated by ChEMBL
Affinity DataKi: 55nMAssay Description:Displacement of [3H]-flunitrazepam from recombinant rat GABAA receptor alpha5beta3gamma2S expressed in HEK293 cell membranes after 90 mins by liquid ...More data for this Ligand-Target Pair
