Compile Data Set for Download or QSAR
Report error Found 63 of affinity data for UniProtKB/TrEMBL: P58295
LigandPNGBDBM50335008(5-Biphenyl-4-yl-4-(2-fluorophenyl)-N-methyl-4H-1,2...)
Affinity DataIC50: 110nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099875((E)-2-Amino-5-(2,4-difluoro-phenyl)-5-(4-isopropyl...)
Affinity DataIC50: 150nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50335010(3-Biphenyl-4-yl-5-ethyl-4-(2-fluorophenyl)-1,2,4-t...)
Affinity DataIC50: 230nMAssay Description:Displacement of [3H]glycine from Wistar rat brain GlyT2 after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50335010(3-Biphenyl-4-yl-5-ethyl-4-(2-fluorophenyl)-1,2,4-t...)
Affinity DataIC50: 230nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50335010(3-Biphenyl-4-yl-5-ethyl-4-(2-fluorophenyl)-1,2,4-t...)
Affinity DataIC50: 230nMAssay Description:Displacement of [3H]glycine from GlyT2 in Wistar rat brainstem cells after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50335006(2-(3-Biphenyl-4-yl-5-methyl-4H-1,2,4-triazole-4-yl...)
Affinity DataIC50: 260nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50335004(3-Biphenyl-4-yl-4-(2-chlorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50: 280nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099886((E)-2-Amino-5-(3,4-diethyl-phenyl)-5-(2,4-difluoro...)
Affinity DataIC50: 283nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099859(Sodium; (E)-2-amino-5-(2-fluoro-phenyl)-5-(4-isopr...)
Affinity DataIC50: 290nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099862(Sodium; (E)-2-amino-5-(2,4-difluoro-phenyl)-5-(4-i...)
Affinity DataIC50: 330nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50335001(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50: 340nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50439743(CHEMBL2419425)
Affinity DataIC50: 340nMAssay Description:Displacement of [3H]glycine from GlyT2 in Wistar rat brainstem cells after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50335001(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50: 340nMAssay Description:Displacement of [3H]glycine from GlyT2 in Wistar rat brainstem cells after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099878((E)-2-Amino-5-(2,4-difluoro-phenyl)-5-naphthalen-2...)
Affinity DataIC50: 365nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50360102(CHEMBL1928735)
Affinity DataIC50: 380nMAssay Description:Displacement of [3H]glycine from Wistar rat brain GlyT2 after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099882(Sodium; (Z)-2-amino-5-(4-isopropyl-phenyl)-5-pheny...)
Affinity DataIC50: 400nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099879(Sodium; (E)-2-amino-5-(2,4-difluoro-phenyl)-5-(4-e...)
Affinity DataIC50: 460nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50335005(3-Biphenyl-4-yl-5-methyl-4-[2-(trifluoromethyl)phe...)
Affinity DataIC50: 600nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099866(Sodium; (E)-2-amino-5-(3,4-diethyl-phenyl)-5-(2,4-...)
Affinity DataIC50: 660nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50439737(CHEMBL2419431)
Affinity DataIC50: 660nMAssay Description:Displacement of [3H]glycine from GlyT2 in Wistar rat brainstem cells after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50335007(2-(3-(biphenyl-4-yl)-5-methyl-4H-1,2,4-triazol-4-y...)
Affinity DataIC50: 680nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50439745(CHEMBL2419423)
Affinity DataIC50: 700nMAssay Description:Displacement of [3H]glycine from GlyT2 in Wistar rat brainstem cells after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099883(Sodium; (E)-2-amino-5-(2,4-difluoro-phenyl)-5-naph...)
Affinity DataIC50: 770nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50335012(3-Biphenyl-4-yl-5-methyl-4-(2-methylphenyl)-4H-1,2...)
Affinity DataIC50: 780nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50439750(CHEMBL2419441)
Affinity DataIC50: 790nMAssay Description:Displacement of [3H]glycine from GlyT2 in Wistar rat brainstem cells after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50439749(CHEMBL2417571)
Affinity DataIC50: 890nMAssay Description:Displacement of [3H]glycine from GlyT2 in Wistar rat brainstem cells after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50335009(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-methoxy-4H-1,...)
Affinity DataIC50: 990nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099858(Sodium; (E)-2-amino-5-(4-isopropyl-phenyl)-5-thiop...)
Affinity DataIC50: 1.03E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099873(Sodium; (E)-2-amino-5-(4-isopropyl-phenyl)-5-(4-me...)
Affinity DataIC50: 1.16E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099863(Sodium; (E)-2-amino-5-(2,4-difluoro-phenyl)-5-p-to...)
Affinity DataIC50: 1.17E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50439744(CHEMBL2419424)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [3H]glycine from GlyT2 in Wistar rat brainstem cells after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50439741(CHEMBL2419427)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [3H]glycine from GlyT2 in Wistar rat brainstem cells after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099868(Sodium; (E)-2-amino-5-biphenyl-3-yl-5-(2,4-difluor...)
Affinity DataIC50: 1.34E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50334998(3-Biphenyl-4-yl-5-methyl-4-phenyl-4H-1,2,4-triazol...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099861(Sodium; (E)-2-amino-5-(2,4-difluoro-phenyl)-5-(3-i...)
Affinity DataIC50: 1.59E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50439751(CHEMBL2419444)
Affinity DataIC50: 1.60E+3nMAssay Description:Displacement of [3H]glycine from GlyT2 in Wistar rat brainstem cells after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50114035(3-Biphenyl-4-yl-4-(2-methoxy-phenyl)-5-methyl-4H-[...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099881((E)-2-Amino-5-(4-tert-butyl-phenyl)-5-(2,4-difluor...)
Affinity DataIC50: 1.74E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099865(Sodium; 2-amino-5,5-bis-(4-isopropyl-phenyl)-pent-...)
Affinity DataIC50: 2.03E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099880(Sodium; (E)-2-amino-5-(2,4-difluoro-phenyl)-5-(4-m...)
Affinity DataIC50: 2.03E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099885(Sodium; (E)-2-amino-5-biphenyl-4-yl-5-(4-isopropyl...)
Affinity DataIC50: 2.06E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099864(Sodium; (Z)-2-amino-5-biphenyl-4-yl-5-(2,4-difluor...)
Affinity DataIC50: 2.40E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099872(Sodium; (E)-2-amino-5-(4-cyano-phenyl)-5-(4-isopro...)
Affinity DataIC50: 2.64E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50360091(CHEMBL1928738)
Affinity DataIC50: 2.70E+3nMAssay Description:Displacement of [3H]glycine from Wistar rat brain GlyT2 after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099870(Sodium; (E)-2-amino-5-biphenyl-2-yl-5-(2,4-difluor...)
Affinity DataIC50: 2.75E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50439740(CHEMBL2419428)
Affinity DataIC50: 3.10E+3nMAssay Description:Displacement of [3H]glycine from GlyT2 in Wistar rat brainstem cells after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50335011(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-isopropyl-4H-...)
Affinity DataIC50: 3.30E+3nMAssay Description:Displacement of [3H]glycine from Wistar rat brain GlyT2 after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50335011(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-isopropyl-4H-...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50099877(Sodium; (E)-2-amino-5-biphenyl-4-yl-5-(2,4-difluor...)
Affinity DataIC50: 3.66E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50360092(CHEMBL1928736)
Affinity DataIC50: 4.20E+3nMAssay Description:Displacement of [3H]glycine from Wistar rat brain GlyT2 after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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