Compile Data Set for Download or QSAR
Report error Found 92 of affinity data for UniProtKB/TrEMBL: P42263
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50017244(CHEMBL73698 | 2-Amino-3-(4-bromo-3-hydroxy-isoxazo...)
Affinity DataEC50:  2.02E+5nMAssay Description:Agonist activity at recombinant GluA3 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126761(2-Amino-3-(5-tert-butyl-3-hydroxy-isothiazol-4-yl)...)
Affinity DataEC50:  3.20E+4nMAssay Description:Electrophysiological data on Xenopus oocytes, expressing homomeric Ionotropic glutamate receptor AMPA 3 (GluR3o)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126764((S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta...)
Affinity DataEC50:  7.20E+3nMAssay Description:Electrophysiological data on Xenopus oocytes, expressing homomeric Ionotropic glutamate receptor AMPA 3 (GluR3o)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126763((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...)
Affinity DataEC50:  7.90E+3nMAssay Description:Electrophysiological data on Xenopus oocytes, expressing homomeric Ionotropic glutamate receptor AMPA 3 (GluR3o)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50002369(Digensaeure | (3S,4R)-3-(carboxymethyl)-4-(prop-1-...)
Affinity DataEC50:  2.66E+4nMAssay Description:Agonist activity at recombinant GluA3 receptor flop isoform expressed in Xenopus oocytes co-expressing gamma2-TARPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50316376(CHEMBL602962 | (S)-2-amino-3-(3-carboxy-5-methyl-4...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at recombinant GluA3 receptor flop isoform expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50017244(CHEMBL73698 | 2-Amino-3-(4-bromo-3-hydroxy-isoxazo...)
Affinity DataEC50:  2.02E+5nMAssay Description:Agonist activity at recombinant GluA3 receptor flop isoform expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataEC50:  2.70E+6nMAssay Description:Agonist activity at recombinant GluA3 receptor flip isoform expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50060635((S)-5-Fluorowillardiine | CHEMBL123132 | Fluorowil...)
Affinity DataEC50:  2.09E+4nMAssay Description:Agonist activity at recombinant GluA3 receptor flip isoform expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50316377((R,S)-6-(2-amino-2-carboxyethyl)-3-hydroxypyridazi...)
Affinity DataEC50:  4.16E+4nMAssay Description:Agonist activity at recombinant GluA3 receptor flip isoform expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50192229(3-Bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-1,1-dioxo-...)
Affinity DataEC50:  1.37E+4nMAssay Description:Activity at human recombinant GluA3 receptor flip isoform expressed in HEK293 cells assessed as effect on glutamate-induced calcium flux by Fluo-4/AM...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50316375(N-[2-(4'-cyanobiphenyl-4-yl)propyl]propane-2-sulfo...)
Affinity DataEC50:  1.66E+3nMAssay Description:Activity at human recombinant GluA3 receptor flip isoform expressed in HEK293 cells assessed as effect on glutamate-induced calcium flux by Fluo-4/AM...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataEC50:  2.70E+6nMAssay Description:Agonist activity at GluA3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50060635((S)-5-Fluorowillardiine | CHEMBL123132 | Fluorowil...)
Affinity DataEC50:  2.09E+4nMAssay Description:Agonist activity at recombinant GluA3 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50316377((R,S)-6-(2-amino-2-carboxyethyl)-3-hydroxypyridazi...)
Affinity DataEC50:  4.16E+4nMAssay Description:Agonist activity at recombinant GluA3 receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataEC50:  3.66E+3nMAssay Description:Agonist activity at recombinant GluA3 receptor flop isoform expressed in Xenopus oocytes co-expressing gamma2-TARPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50512943(CHEMBL4448290)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at GluA3 receptor (unknown origin) expressed in HEK293 cells assessed induction of S-glutamate-induced calcium flux measured after 9...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataEC50:  2.40E+4nMAssay Description:Agonist activity at GluA3 receptor (unknown origin) expressed in HEK293 cells assessed induction of S-glutamate-induced calcium flux measured after 9...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50512940(CHEMBL3742450)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at GluA3 receptor (unknown origin) expressed in HEK293 cells assessed induction of S-glutamate-induced calcium flux measured after 9...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataEC50:  2.34E+4nMAssay Description:Agonist activity at GluA3 receptor (unknown origin) expressed in HEK293 cells assessed induction of S-glutamate-induced calcium flux measured after 9...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50059674((RS)-2-amino-3-[3-hydroxy-5-(1-methyl-2H-5-tetrazo...)
Affinity DataEC50: >3.00E+6nMAssay Description:Agonist activity at GluR3 expressed in HEK293 cells by Fluo-4/Ca2+ assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataEC50:  6.70E+4nMAssay Description:Agonist activity at GluR3 expressed in HEK293 cells by Fluo-4/Ca2+ assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50211399((RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazo...)
Affinity DataEC50:  1.00E+6nMAssay Description:Agonist activity at GluR3 expressed in HEK293 cells by Fluo-4/Ca2+ assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50166285((RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazo...)
Affinity DataEC50:  4.50E+5nMAssay Description:Agonist activity at GluR3 expressed in HEK293 cells by Fluo-4/Ca2+ assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataEC50:  3.50E+4nMAssay Description:Agonist activity at recombinant GluA3 receptor flop isoform expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50094024(propane-2-sulfonic acid [2-(4'-cyano-biphenyl-4-yl...)
Affinity DataEC50:  1.66E+3nMAssay Description:Inhibition of GluR3 expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50166287((RS)-2-amino-3-[3-hydroxy-5-(2-isopropyl-2H-5-tetr...)
Affinity DataEC50:  7.00E+5nMAssay Description:Agonist activity at GluR3 expressed in HEK293 cells by Fluo-4/Ca2+ assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50166286((RS)-2-amino-3-[3-hydroxy-5-(2-ethyl-2H-5-tetrazol...)
Affinity DataEC50:  1.80E+4nMAssay Description:Agonist activity at GluR3 expressed in HEK293 cells by Fluo-4/Ca2+ assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50105843(Joro spider toxin 3 | 2-Amino-N-{3-[4-(3-amino-pro...)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant GluA3 receptor flop isoform expressed in Xenopus oocytes assessed as inhibition of 300 uM kainate-induced current by patch ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant GluA3 receptor flip isoform expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current by patch ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 230nMAssay Description:Inhibition of GluA3 receptor expressed in Xenopus oocytes assessed as inhibition of 100 uM kainate-induced current by patch clamp electrophysiologica...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxali...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50184410(CHEBI:71013 | E-2007 | E2007 | ER-155055-90 | Fyco...)
Affinity DataIC50: 2.10E+3nMAssay Description:Blockade of whole cell current in GluA3i-G (unknown origin) transfected in HEK293 cells measured at -60 mV in presence of glutamate by whole cell pat...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against Ionotropic glutamate receptor AMPA 3 of HEK293 cells in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50137125(2-(3-(3-bromophenyl)ureido)-4-chlorobenzoic acid |...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against Ionotropic glutamate receptor AMPA 3 of HEK293 cells in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50166288((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...)
Affinity DataKi:  2.24nMAssay Description:Binding affinity for ionotropic Glutamate receptor AMPA 3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50002370((RS)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)-p...)
Affinity DataKi:  12nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM17662(CHEMBL276815 | 2-amino-3-(3-hydroxy-5-methyl-4-iso...)
Affinity DataKi:  20.6nMAssay Description:Binding affinity for ionotropic Glutamate receptor AMPA 3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50002370((RS)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)-p...)
Affinity DataKi:  21nMAssay Description:Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 3 (GluR3) expressed in Sf 9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM85214(glutamate-AMPA)
Affinity DataKi:  21nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50166286((RS)-2-amino-3-[3-hydroxy-5-(2-ethyl-2H-5-tetrazol...)
Affinity DataKi:  44.8nMAssay Description:Binding affinity for ionotropic Glutamate receptor AMPA 3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50289498(3-Hydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxalin-2...)
Affinity DataKi:  49nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50373890(CHEMBL429594)
Affinity DataKi:  160nMAssay Description:Binding affinity at iGluR3o receptor expressed in sf9 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50060635((S)-5-Fluorowillardiine | CHEMBL123132 | Fluorowil...)
Affinity DataKi:  179nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataKi:  254nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50289498(3-Hydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxalin-2...)
Affinity DataKi:  310nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50289498(3-Hydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxalin-2...)
Affinity DataKi:  380nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50289504(7-Cyano-3-hydroxy-6-nitro-quinoxalin-2-ol anion | ...)
Affinity DataKi:  402nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM85216(Dnal,Cys,Tyr,DTrp,Lys,Val,Cys,Nal-nh2)
Affinity DataKi:  494nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutamate receptor 3(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM84949(CAS_3035216 | NSC_3035216 | YM90k)
Affinity DataKi:  630nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
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