Compile Data Set for Download or QSAR
Report error Found 131 of affinity data for UniProtKB/TrEMBL: P35377
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333103(CHEMBL1631931)
Affinity DataKd:  1.95nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333095(CHEMBL1631923)
Affinity DataEC50:  0.610nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333096(CHEMBL1631924)
Affinity DataEC50:  14nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333097(CHEMBL1631925)
Affinity DataEC50:  30nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333098(CHEMBL1631926)
Affinity DataEC50:  0.0400nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333098(CHEMBL1631926)
Affinity DataEC50:  1nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose in presence of compound 14 by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333104(H-FGGFTGARKSARKLANQ-NH2 | N/OFQ-NH2 | NC(1-17)NH2 ...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50106479(FGGFTGARKSARK | H-FGGFTGARKSARK-NH2 | NC(1-13)NH2 ...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333105(H-FGGF(4-F)TGARKSARKLKNQ-NH2 | CHEMBL1631909)
Affinity DataEC50:  0.360nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333106(H-FGGFTGK(Ac)RKSNRKK(Ac)ANQN-NH2 | CHEMBL1631920)
Affinity DataEC50:  355nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333107(H-FGGFTGARKSARKAANQA-NH2 | CHEMBL1631921)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333108(CHEMBL1631922)
Affinity DataEC50:  3.10nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phosphorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50411362(CHEMBL437744)
Affinity DataKd:  0.794nMAssay Description:Antagonist activity at NOP receptor in Swiss mouse vas deferens by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50475328(CHEMBL414782)
Affinity DataEC50:  0.437nMAssay Description:Inhibition of electrically evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50475327(CHEMBL410653)
Affinity DataEC50:  0.759nMAssay Description:Inhibition of electrically evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50475330(CHEMBL442297)
Affinity DataEC50:  1nMAssay Description:Inhibition of electrically evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50004178(Nociceptin | Nociceptin/orphanin FQ | ORPHANIN FQ)
Affinity DataEC50:  5.40nMAssay Description:Inhibition of electrically evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50475333(CHEMBL264846)
Affinity DataEC50:  2.60nMAssay Description:Inhibition of electrically evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333103(CHEMBL1631931)
Affinity DataIC50: 7.5nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333102(CHEMBL1631930)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333100(BzLGlyGGF(4-F)TGARKSARKLKNQ-NH2 | CHEMBL1631928)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333099(BzLGlyGGFTGARKSARKLKNQ-NH2 | CHEMBL1631927)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50417550(CHEMBL1631919)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50417551(CHEMBL1631932)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50417552(CHEMBL1631934)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50417553(CHEMBL1631933)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333101(BzLGlyGGFTGARKSARK-NH2 | CHEMBL1631929)
Affinity DataIC50: 755nMAssay Description:Antagonist activity at NOR in mouse Neuro-2a cells assessed as inhibition of nociceptin-induced ERK phosphorylation administered for 15 mins before n...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM85821(OFQ/N,Iodo[Tyr14])
Affinity DataKi:  0.00600nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM21842(OFQ 1-17 | N/OFQ | (2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-...)
Affinity DataKi:  0.00700nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50274460(CHEMBL504540 | OFQ/N,[Tyr14] | FGGFTGARKSARKYANQ)
Affinity DataKi:  0.00700nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM85821(OFQ/N,Iodo[Tyr14])
Affinity DataKi:  0.120nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM21842(OFQ 1-17 | N/OFQ | (2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-...)
Affinity DataKi:  0.170nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50473478(CHEMBL409204)
Affinity DataKi:  0.302nMAssay Description:Inhibition of [3H]NC-NH2 binding to mouse forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM86660(OFQ/N UFP-102)
Affinity DataKi:  0.360nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM86660(OFQ/N UFP-102)
Affinity DataKi:  0.380nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50473476(CHEMBL261997)
Affinity DataKi:  0.398nMAssay Description:Inhibition of [3H]NC-NH2 binding to mouse forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM21842(OFQ 1-17 | N/OFQ | (2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-...)
Affinity DataKi:  0.430nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM85823(OFQ/N (1-11), Iodo[Tyr10])
Affinity DataKi:  0.580nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM85194(Ac-RYYRWR-NH2)
Affinity DataKi:  0.600nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50473477(CHEMBL427791)
Affinity DataKi:  0.603nMAssay Description:Inhibition of [3H]NC-NH2 binding to mouse forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM86660(OFQ/N UFP-102)
Affinity DataKi:  0.650nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50274460(CHEMBL504540 | OFQ/N,[Tyr14] | FGGFTGARKSARKYANQ)
Affinity DataKi:  0.650nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM85191(CAS_200959-47-3 | Ac-RYYRWK-NH2)
Affinity DataKi:  0.710nMMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50473474(CHEMBL405648)
Affinity DataKi:  0.794nMAssay Description:Inhibition of [3H]NC-NH2 binding to mouse forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50106479(FGGFTGARKSARK | H-FGGFTGARKSARK-NH2 | NC(1-13)NH2 ...)
Affinity DataKi:  0.794nMAssay Description:Affinity to nociceptin receptors on mouse forebrain membranes by [3H]NC-NH2 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50333104(H-FGGFTGARKSARKLANQ-NH2 | N/OFQ-NH2 | NC(1-17)NH2 ...)
Affinity DataKi:  0.794nMAssay Description:Affinity to nociceptin receptors on mouse forebrain membranes by [3H]NC-NH2 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50473472(CHEMBL412537)
Affinity DataKi:  0.891nMAssay Description:Inhibition of [3H]NC-NH2 binding to mouse forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50106479(FGGFTGARKSARK | H-FGGFTGARKSARK-NH2 | NC(1-13)NH2 ...)
Affinity DataKi:  0.912nMAssay Description:Inhibition of [3H]NC-NH2 binding to mouse forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50473482(CHEMBL265544)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]NC-NH2 binding to mouse forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNociceptin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50472736(CHEMBL406905)
Affinity DataKi:  1nMAssay Description:Affinity to nociceptin receptors on mouse forebrain membranes by [3H]NC-NH2 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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