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Report error Found 155 of affinity data for UniProtKB/TrEMBL: P34896
TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM18796((2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-...)
Affinity DataKd:  1.69E+4nMAssay Description:Binding affinity to human recombinant Serine hydroxymethyltransferase, cytosolic by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285658(US10077273, Compound 4 | US10584132, Compound 4 | ...)
Affinity DataIC50: 0.170nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285663(US10077273, Compound 11 | US10584132, Compound 11 ...)
Affinity DataIC50: 0.400nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285663(US10077273, Compound 11 | US10584132, Compound 11 ...)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285659(US10077273, Compound 68 | US10584132, Compound 68 ...)
Affinity DataIC50: 0.400nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285660(US10077273, Compound 1 | US10584132, Compound 1 | ...)
Affinity DataIC50: 0.650nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285660(US10077273, Compound 1 | US10584132, Compound 1 | ...)
Affinity DataIC50: 0.790nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285661(US10077273, Compound 69 | US10584132, Compound 69 ...)
Affinity DataIC50: 0.800nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285662(US10077273, Compound 70 | US10584132, Compound 70 ...)
Affinity DataIC50: 1nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285663(US10077273, Compound 11 | US10584132, Compound 11 ...)
Affinity DataIC50: 1.40nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285659(US10077273, Compound 68 | US10584132, Compound 68 ...)
Affinity DataIC50: 1.70nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285659(US10077273, Compound 68 | US10584132, Compound 68 ...)
Affinity DataIC50: 1.70nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285664(US10077273, Compound 71 | US10584132, Compound 71 ...)
Affinity DataIC50: 1.70nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285666(US10077273, Compound 2 | US10584132, Compound 2 | ...)
Affinity DataIC50: 2nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285666(US10077273, Compound 2 | US10584132, Compound 2 | ...)
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285665(US10077273, Compound 72 | US10584132, Compound 72 ...)
Affinity DataIC50: 2nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285664(US10077273, Compound 71 | US10584132, Compound 71 ...)
Affinity DataIC50: 2.40nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285664(US10077273, Compound 71 | US10584132, Compound 71 ...)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285665(US10077273, Compound 72 | US10584132, Compound 72 ...)
Affinity DataIC50: 4nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285665(US10077273, Compound 72 | US10584132, Compound 72 ...)
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285666(US10077273, Compound 2 | US10584132, Compound 2 | ...)
Affinity DataIC50: 4nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285686(US10077273, Compound HK-16 | US10077273, Compound ...)
Affinity DataIC50: 5nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285686(US10077273, Compound HK-16 | US10077273, Compound ...)
Affinity DataIC50: 5nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285688(US10077273, Compound HK-X2 | US10934305, Compound ...)
Affinity DataIC50: 5nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285667(US10077273, Compound 73 | US10584132, Compound 73 ...)
Affinity DataIC50: 7.5nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285689(US10077273, Compound HK-X3 | US10934305, Compound ...)
Affinity DataIC50: 7.80nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285668(US10077273, Compound 8 | US10584132, Compound 8 | ...)
Affinity DataIC50: 8nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285668(US10077273, Compound 8 | US10584132, Compound 8 | ...)
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285687(US10077273, Compound HK-X1 | US10934305, Compound ...)
Affinity DataIC50: 13nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285688(US10077273, Compound HK-X2 | US10934305, Compound ...)
Affinity DataIC50: 13nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM485192(US10934305, Compound HK-16 (PK-2))
Affinity DataIC50: 15nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285689(US10077273, Compound HK-X3 | US10934305, Compound ...)
Affinity DataIC50: 16.9nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285669(US10077273, Compound 74 | US10584132, Compound 74 ...)
Affinity DataIC50: 17nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285669(US10077273, Compound 74 | US10584132, Compound 74 ...)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285669(US10077273, Compound 74 | US10584132, Compound 74 ...)
Affinity DataIC50: 19nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285685(US10077273, Compound HK-15 | US10934305, Compound ...)
Affinity DataIC50: 20nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285686(US10077273, Compound HK-16 | US10077273, Compound ...)
Affinity DataIC50: 21nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285686(US10077273, Compound HK-16 | US10077273, Compound ...)
Affinity DataIC50: 27nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285685(US10077273, Compound HK-15 | US10934305, Compound ...)
Affinity DataIC50: 35nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285690(US10077273, Compound a | 6-amino-4-(3-bromo-5-(tri...)
Affinity DataIC50: 42nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285668(US10077273, Compound 8 | US10584132, Compound 8 | ...)
Affinity DataIC50: 43nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285687(US10077273, Compound HK-X1 | US10934305, Compound ...)
Affinity DataIC50: 66nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285684(US10077273, Compound HK-14 | US10934305, Compound ...)
Affinity DataIC50: 67nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285685(US10077273, Compound HK-15 | US10934305, Compound ...)
Affinity DataIC50: 100nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285684(US10077273, Compound HK-14 | US10934305, Compound ...)
Affinity DataIC50: 131nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285682(US10077273, Compound HK-12 | US10934305, Compound ...)
Affinity DataIC50: 168nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285682(US10077273, Compound HK-12 | US10934305, Compound ...)
Affinity DataIC50: 206nMpH: 7.4Assay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285677(US10077273, Compound HK-7 | US10934305, Compound H...)
Affinity DataIC50: 400nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM485179(US10934305, Compound HK-5 | US10934305, Compound H...)
Affinity DataIC50: 400nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM285683(US10077273, Compound HK-13 | US10934305, Compound ...)
Affinity DataIC50: 500nMAssay Description:For the SHMT1 and SHMT2 in vitro enzymatic assays, the rate of 5,10-methylene tetrahydrofolate formation catalyzed by SHMT1/2 was indirectly evaluate...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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