Compile Data Set for Download or QSAR
Report error Found 906 for UniProtKB: P28564
Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM84737(CAS_127792-75-0 | CP-93129 | CHEMBL304008 | 3-(1,2...)
Affinity DataEC50:  56nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigraMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  26nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigraMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM85099(SDZ SER 082 FUMARATE | CAS_141474-54-6 | SDZ SER-0...)
Affinity DataKd:  199nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2C receptor of porcine choroid plexus using [3H]mesulergineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM85099(SDZ SER 082 FUMARATE | CAS_141474-54-6 | SDZ SER-0...)
Affinity DataKd:  200nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2C receptor of porcine choroid plexus using [3H]mesulergineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGUS20250019357, Compound S-5-MAPB(US11767305, Compound S-5-MAPB)
Affinity DataEC50:  161nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGUS20250019357, Compound R-5-MAPB(US11767305, Compound R-5-MAPB)
Affinity DataEC50:  981nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGUS20250019357, Compound S-6-MAPB(US11767305, Compound S-6-MAPB)
Affinity DataEC50:  102nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGUS20250019357, Compound R-6-MAPB(US11767305, Compound R-6-MAPB)
Affinity DataEC50:  1.48E+3nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM712787(US20250019357, Compound rac-5-MBPB)
Affinity DataEC50:  5.82E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM712788(US20250019357, Compound S-5-MBPB)
Affinity DataEC50:  3.06E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM712789(US20250019357, Compound R-5-MBPB)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM712791(US20250019357, Compound rac-6-MBPB)
Affinity DataEC50:  1.95E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM712792(US20250019357, Compound S-6-MBPB)
Affinity DataEC50:  1.72E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM712796(US20250019357, Compound R-6-MBPB)
Affinity DataEC50:  5.75E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM712797(US20250019357, Compound rac-BK-5-MAPB)
Affinity DataEC50:  140nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGUS20250019357, Compound (-)-BK-5-MAPB(US11767305, Compound (-)-BK-5-MAPB)
Affinity DataEC50:  77.7nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGUS20250019357, Compound (+)-BK-5-MAPB(US11767305, Compound (+)-BK-5-MAPB)
Affinity DataEC50:  3.07E+3nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM712800(US20250019357, Compound rac-BK-6-MAPB)
Affinity DataEC50:  537nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGUS20250019357, Compound (-)-BK-6-MAPB(US11767305, Compound (-)-BK-6-MAPB)
Affinity DataEC50:  288nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGUS20250019357, Compound (+)-BK-6-MAPB(US11767305, Compound (+)-BK-6-MAPB)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM712803(US20250019357, Compound rac-BK-5-MBPB)
Affinity DataEC50:  1.96E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGUS20250019357, Compound (-)-BK-5-MBPB(US11767305, Compound R-5-MBPB)
Affinity DataEC50:  6.61E+3nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGUS20250019357, Compound (+)-BK-5-MBPB(US11767305, Compound S-5-MBPB)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM712806(US20250019357, Compound rac-BK-6-MBPB)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM712807(US20250019357, Compound (-)-BK-6-MBPB)
Affinity DataEC50:  7.52E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM712809(US20250019357, Compound (+)-BK-6-MBPB)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50084952(4'-Carbamimidoyl-2'-methyl-biphenyl-4-carboxylic a...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50280830(3-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 0.5nMAssay Description:Compound was evaluated for inhibition of 5-HT uptake by measuring its ability to inhibit [3H]paroxetine binding to rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015711(CHEMBL26379 | 3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigraMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50084958(2'-Methyl-4'-(5-methyl-[1,3,4]oxadiazol-2-yl)-biph...)
Affinity DataIC50: 0.930nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50280826(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 1nMAssay Description:Compound was evaluated for inhibition of 5-HT uptake by measuring its ability to inhibit [3H]paroxetine binding to rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50280822(4-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 1.10nMAssay Description:Compound was evaluated for inhibition of 5-HT uptake by measuring its ability to inhibit [3H]paroxetine binding to rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015714(CHEMBL26378 | 3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigraMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50047098(RP-68303 | 1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-...)
Affinity DataIC50: 1.20nMAssay Description:Compound was evaluated for inhibition of 5-HT uptake by measuring its ability to inhibit [3H]paroxetine binding to rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50084953(2-Methyl-biphenyl-4,4'-dicarboxylic acid 4-amide 4...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50280819(1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 1.5nMAssay Description:Compound was evaluated for inhibition of 5-HT uptake by measuring its ability to inhibit [3H]paroxetine binding to rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM79215(SMR001230745 | N-[4-methoxy-3-(4-methylpiperazin-1...)
Affinity DataIC50: 1.60nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM79215(SMR001230745 | N-[4-methoxy-3-(4-methylpiperazin-1...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50280831(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 1.80nMAssay Description:Compound was evaluated for inhibition of 5-HT uptake by measuring its ability to inhibit [3H]paroxetine binding to rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015712(CHEMBL26906 | 5-Fluoro-3-(1,2,3,6-tetrahydro-pyrid...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigraMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM81498(5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-i...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigraMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50084959(4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)pheny...)
Affinity DataIC50: 2nMAssay Description:Inhibition affinity against 5-HT-1B receptor in rat frontal cortex using radio binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50086096(N-(2,3-Dihydro-1'-methylspiro[benzofuran-3,4'-pipe...)
Affinity DataIC50: 2.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor in rat frontal cortex using [125I]iodocyanopindolol as radio-ligand.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50280817(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 2.10nMAssay Description:Compound was evaluated for inhibition of 5-HT uptake by measuring its ability to inhibit [3H]paroxetine binding to rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50016966(CHEMBL543967 | 1,1-Dioxo-2-[4-(4-thieno[3,2-c]pyri...)
Affinity DataIC50: 2.30nMAssay Description:Ability to bind at 5-hydroxytryptamine 1 receptor of rat hippocampus by displacing [3H]5-HTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50280828(3-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 2.60nMAssay Description:Compound was evaluated for inhibition of 5-HT uptake by measuring its ability to inhibit [3H]paroxetine binding to rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50227493(CHEMBL288111)
Affinity DataIC50: 3nMAssay Description:Tested for its binding affinity towards 5-hydroxytryptamine 1 receptor in rat cortical membrane homogenates using radioligand ([3H]5-HT) binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50280824(1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 3.10nMAssay Description:Compound was evaluated for inhibition of 5-HT uptake by measuring its ability to inhibit [3H]paroxetine binding to rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article

Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015709(CHEMBL27592 | 5-Bromo-3-(1,2,3,6-tetrahydro-pyridi...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigraMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015717(CHEMBL282994 | 5-Chloro-3-(1,2,3,6-tetrahydro-pyri...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of Forskolin-stimulated adenylate cyclase activity against 5-hydroxytryptamine 1B receptor of rat substantia nigraMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 906 total ) | Next | Last >>
Jump to: