Compile Data Set for Download or QSAR
Report error Found 3390 for UniProtKB: P25090
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21692(1-(4-chlorophenyl)-3-[1-methyl-5-(1-methylethyl)-3...)
Affinity DataEC50:  44nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21693(CHEMBL377169 | 1-(2-chlorophenyl)-3-[1-methyl-3-ox...)
Affinity DataEC50: >1.00E+4nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21694(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  6.39E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21695(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  5.10E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21696(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  1.02E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21697(2-ethyl-1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]pi...)
Affinity DataEC50:  690nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21698(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  830nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21699(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  1.52E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21700(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Affinity DataEC50:  2.71E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21701(racemic mixture | 2-ethyl-1-{1-[(5-methoxy-1H-indo...)
Affinity DataEC50:  130nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21702(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-indol-2-yl)carbon...)
Affinity DataEC50:  34nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21703(2-ethyl-1-[(3S)-1-[(5-methoxy-1H-indol-2-yl)carbon...)
Affinity DataEC50:  3.50E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21704(2-ethyl-1-[(3R)-1-[(5-fluoro-1H-indol-2-yl)carbony...)
Affinity DataEC50:  1.49E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21705(1-[(3R)-1-[(5-chloro-1H-indol-2-yl)carbonyl]pyrrol...)
Affinity DataEC50:  1.41E+4nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21706(1-[(3R)-1-[(5-bromo-1H-indol-2-yl)carbonyl]pyrroli...)
Affinity DataEC50:  810nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21707(2-ethyl-1-[(3R)-1-{[5-(trifluoromethoxy)-1H-indol-...)
Affinity DataEC50:  1.22E+4nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21708(2-ethyl-1-[(3R)-1-[(5-ethyl-1H-indol-2-yl)carbonyl...)
Affinity DataEC50:  270nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM21709(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-1,3-benzodiazol-2...)
Affinity DataEC50:  1.87E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM230850(US9346793, 1)
Affinity DataEC50:  11.8nMAssay Description:Cells expressing recombinant human ALX receptor and the G-protein Gα16 (HEK293-hALXR-Gα16) were grown to 80% confluency in Growing Medium (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM230851(US9346793, 2)
Affinity DataEC50:  7.60nMAssay Description:Cells expressing recombinant human ALX receptor and the G-protein Gα16 (HEK293-hALXR-Gα16) were grown to 80% confluency in Growing Medium (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM230852(US9346793, 3)
Affinity DataEC50:  8nMAssay Description:Cells expressing recombinant human ALX receptor and the G-protein Gα16 (HEK293-hALXR-Gα16) were grown to 80% confluency in Growing Medium (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM230853(US9346793, 4)
Affinity DataEC50:  51nMAssay Description:Cells expressing recombinant human ALX receptor and the G-protein Gα16 (HEK293-hALXR-Gα16) were grown to 80% confluency in Growing Medium (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM230854(US9346793, 5)
Affinity DataEC50:  21.7nMAssay Description:Cells expressing recombinant human ALX receptor and the G-protein Gα16 (HEK293-hALXR-Gα16) were grown to 80% confluency in Growing Medium (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM230855(US9346793, 6)
Affinity DataEC50:  12.7nMAssay Description:Cells expressing recombinant human ALX receptor and the G-protein Gα16 (HEK293-hALXR-Gα16) were grown to 80% confluency in Growing Medium (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM230856(US9346793, 7)
Affinity DataEC50:  10.1nMAssay Description:Cells expressing recombinant human ALX receptor and the G-protein Gα16 (HEK293-hALXR-Gα16) were grown to 80% confluency in Growing Medium (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM230857(US9346793, 8)
Affinity DataEC50:  17.8nMAssay Description:Cells expressing recombinant human ALX receptor and the G-protein Gα16 (HEK293-hALXR-Gα16) were grown to 80% confluency in Growing Medium (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM230858(US9346793, 9)
Affinity DataEC50:  17.2nMAssay Description:Cells expressing recombinant human ALX receptor and the G-protein Gα16 (HEK293-hALXR-Gα16) were grown to 80% confluency in Growing Medium (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM230859(US9346793, 10)
Affinity DataEC50:  10.3nMAssay Description:Cells expressing recombinant human ALX receptor and the G-protein Gα16 (HEK293-hALXR-Gα16) were grown to 80% confluency in Growing Medium (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM230860(US9346793, 11)
Affinity DataEC50:  82.3nMAssay Description:Cells expressing recombinant human ALX receptor and the G-protein Gα16 (HEK293-hALXR-Gα16) were grown to 80% confluency in Growing Medium (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM230861(US9346793, 12)
Affinity DataEC50:  32.3nMAssay Description:Cells expressing recombinant human ALX receptor and the G-protein Gα16 (HEK293-hALXR-Gα16) were grown to 80% confluency in Growing Medium (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM230862(US9346793, 13)
Affinity DataEC50:  13.2nMAssay Description:Cells expressing recombinant human ALX receptor and the G-protein Gα16 (HEK293-hALXR-Gα16) were grown to 80% confluency in Growing Medium (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM230863(US9346793, 14)
Affinity DataEC50:  11.3nMAssay Description:Cells expressing recombinant human ALX receptor and the G-protein Gα16 (HEK293-hALXR-Gα16) were grown to 80% confluency in Growing Medium (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM230864(US9346793, 15)
Affinity DataEC50:  52.9nMAssay Description:Cells expressing recombinant human ALX receptor and the G-protein Gα16 (HEK293-hALXR-Gα16) were grown to 80% confluency in Growing Medium (...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295527(2-[5-(3-Methoxybenzyl)-3-methyl-6-oxo-6H-pyridazin...)
Affinity DataEC50:  600nMAssay Description:Agonist activity at FPRL1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295519(N-(3,4-Dimethoxyphenyl)-2-[5-(3-methoxybenzyl)-3-m...)
Affinity DataEC50:  1.68E+4nMAssay Description:Agonist activity at FPRL1 expressed in human HL60 cells assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295521(2-[5-(3-Methoxybenzyl)-3-methyl-6-oxo-6H-pyridazin...)
Affinity DataEC50:  8.80E+3nMAssay Description:Agonist activity at FPRL1 expressed in human HL60 cells assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295517(2-[5-(3-Methoxybenzyl)-3-methyl-6-oxo-6H-pyridazin...)
Affinity DataEC50:  900nMAssay Description:Agonist activity at FPRL1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295517(2-[5-(3-Methoxybenzyl)-3-methyl-6-oxo-6H-pyridazin...)
Affinity DataEC50:  900nMAssay Description:Agonist activity at FPRL1 in human neutrophiles by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295521(2-[5-(3-Methoxybenzyl)-3-methyl-6-oxo-6H-pyridazin...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at FPRL1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295519(N-(3,4-Dimethoxyphenyl)-2-[5-(3-methoxybenzyl)-3-m...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at FPRL1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295524(N-(4-Bromophenyl)-2-[5-(3-methoxybenzyl)-3-methyl-...)
Affinity DataEC50:  3.80E+3nMAssay Description:Agonist activity at FPRL1 expressed in human HL60 cells assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295520(N-Benzo[1,3]dioxol-5-yl-2-[5-(3-methoxybenzyl)-3-m...)
Affinity DataEC50:  4.50E+3nMAssay Description:Agonist activity at FPRL1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295514(N-(4-Chlorophenyl)-2-[5-(3-methoxybenzyl)-3-methyl...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at FPRL1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295524(N-(4-Bromophenyl)-2-[5-(3-methoxybenzyl)-3-methyl-...)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at FPRL1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295526(N-(4-Bromophenyl)-2-[5-(3-methoxybenzyl)-3-methyl-...)
Affinity DataEC50:  600nMAssay Description:Agonist activity at FPRL1 in human neutrophiles by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295514(N-(4-Chlorophenyl)-2-[5-(3-methoxybenzyl)-3-methyl...)
Affinity DataEC50:  4.00E+3nMAssay Description:Agonist activity at FPRL1 expressed in human HL60 cells assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295515(N-(4-Iodophenyl)-2-[5-(3-methoxybenzyl)-3-methyl-6...)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at FPRL1 in human neutrophiles by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295525(N-(4-Bromophenyl)-3-[3-(3-methoxybenzyl)-5-methyl-...)
Affinity DataEC50:  1.18E+4nMAssay Description:Agonist activity at FPRL1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295515(N-(4-Iodophenyl)-2-[5-(3-methoxybenzyl)-3-methyl-6...)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at FPRL1 in human neutrophiles assessed as induction of intracellular calcium flux by FLIPR3 calcium assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetN-formyl peptide receptor 2(Human)
Amgen

LigandPNGBDBM50295525(N-(4-Bromophenyl)-3-[3-(3-methoxybenzyl)-5-methyl-...)
Affinity DataEC50:  1.18E+4nMAssay Description:Agonist activity at FPRL1 in human neutrophiles by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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