Compile Data Set for Download or QSAR
Report error Found 1048 of affinity data for UniProtKB/TrEMBL: P25021
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127601(2-(1H-Imidazol-4-yl)-cyclopropylamine | CHEMBL5938...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127602(C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine |...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127603(C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine |...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127610((1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclo...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127609(C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine |...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127604(C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine |...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127606(2-(1H-Imidazol-4-yl)-cyclopropylamine | CHEMBL2940...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50413505(CHEMBL515428)
Affinity DataEC50:  83nMAssay Description:Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM7966([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50413501(SK&F-91486 | SK-91486 | CHEMBL325327)
Affinity DataEC50:  2.57E+3nMAssay Description:Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50413508(CHEMBL474448)
Affinity DataEC50:  288nMAssay Description:Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50413503(UR-PI141 | CHEMBL514641)
Affinity DataEC50:  81nMAssay Description:Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50413502(UR-PI104 | CHEMBL474447)
Affinity DataEC50:  36nMAssay Description:Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50377986(UR-AK24 | CHEMBL483406)
Affinity DataEC50:  68nMAssay Description:Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50413504(CHEMBL474449)
Affinity DataEC50:  955nMAssay Description:Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50413500(UR-PI287 | CHEMBL471724)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50413499(UR-PI295 | CHEMBL465170)
Affinity DataEC50:  141nMAssay Description:Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50413506(UR-PI147 | CHEMBL474617)
Affinity DataEC50:  347nMAssay Description:Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50413507(UR-PI182 | CHEMBL475620)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50413497(UR-PI288 | CHEMBL443896)
Affinity DataEC50:  724nMAssay Description:Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50413498(UR-PI294 | CHEMBL475621)
Affinity DataEC50:  372nMAssay Description:Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127607(VUF-5296 | 2-(1H-Imidazol-4-yl)-cyclopropylamine |...)
Affinity DataEC50:  2.50E+3nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127608(2-[2-(1H-Imidazol-4-yl)-cyclopropyl]-ethylamine | ...)
Affinity DataEC50:  93nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127605(VUF-5297 | (1S,2S)-2-(1H-Imidazol-4-yl)-cyclopropy...)
Affinity DataEC50:  696nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM7966([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...)
Affinity DataEC50:  463nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50187891(2-[(1E,3E)-5-[(2E)-1-[5-({2-[(Z)-[(cyanoamino)({3-...)
Affinity DataEC50:  160nMAssay Description:Agonist activity at human H2RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50194202((1S,2R)-trans-2-[2-(cyclohexylmethylamino)ethyl]-1...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human H2 receptor expressed in 293-EBNA cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM7966([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...)
Affinity DataEC50:  650nMAssay Description:Agonist activity at human H2 receptor expressed in 293-EBNA cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50194208((1S,2R)-trans-2-[2-(4-chlorobenzylamino)ethyl]-1-(...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human H2 receptor expressed in 293-EBNA cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50194205((1R,2S)-trans-2-[2-(4-chlorobenzylamino)ethyl]-1-(...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human H2 receptor expressed in 293-EBNA cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50170116(CHEMBL3805813)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human histamine H2 receptor expressed in sf9 cell membrane co-expressing Gsalphas incubated for 90 mins by [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50170117(CHEMBL3805995)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human histamine H2 receptor expressed in sf9 cell membrane co-expressing Gsalphas incubated for 90 mins by [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50319285(5-fluoro-4-methyl-2-(2-methyl-4-(3-((4aR,7aR)-tetr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Displacement of [125I]APT from human recombinant histamine H2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50319300(N-(2-(1H-imidazol-4-yl)ethyl)-3-(4-(5-fluoro-4-met...)
Affinity DataEC50: >1.00E+4nMAssay Description:Displacement of [125I]APT from human recombinant histamine H2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50319302(5-(3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-y...)
Affinity DataEC50:  131nMAssay Description:Displacement of [125I]APT from human recombinant histamine H2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394708(CHEMBL2165629)
Affinity DataEC50:  151nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394703(CHEMBL2165628)
Affinity DataEC50:  7.59nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394709(CHEMBL2165645)
Affinity DataEC50:  13.8nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394705(CHEMBL2165643)
Affinity DataEC50:  24.6nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394694(CHEMBL2165642)
Affinity DataEC50:  6.17nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394706(CHEMBL2165641)
Affinity DataEC50:  56.2nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394707(CHEMBL2165640)
Affinity DataEC50:  214nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394711(CHEMBL2165638)
Affinity DataEC50:  93.3nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394712(CHEMBL2165637)
Affinity DataEC50:  21.4nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394713(CHEMBL2165636)
Affinity DataEC50:  30.9nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394696(CHEMBL2165634)
Affinity DataEC50:  25.7nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394697(CHEMBL2165633)
Affinity DataEC50:  16.6nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394698(CHEMBL2165632)
Affinity DataEC50:  7.76nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394699(CHEMBL2165631)
Affinity DataEC50:  44.7nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394700(CHEMBL2165630)
Affinity DataEC50:  47.9nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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