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TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataKd:  13nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKd:  36nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKd:  7nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKd:  26nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKd:  42nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataKd:  40nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataKd:  30nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKd:  51nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDimer of Retinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKd:  28nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDimer of Retinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKd:  18nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50012902(CHEMBL3261318 | USRE46024, 1)
Affinity DataEC50:  7.75E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50012859(CHEMBL3261319 | USRE46024, 2)
Affinity DataEC50:  7.31E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50012912(CHEMBL3261321 | USRE46024, 3)
Affinity DataEC50:  519nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50012901(CHEMBL3261320 | USRE46024, 4)
Affinity DataEC50:  2.33E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50012916(CHEMBL3261322 | USRE46024, 5)
Affinity DataEC50:  699nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50012918(CHEMBL3261324 | USRE46024, 6)
Affinity DataEC50:  666nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM60964(USRE46024, 7)
Affinity DataEC50:  117nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50012905(CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...)
Affinity DataEC50:  192nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50012915(CHEMBL3261335 | USRE46024, 9)
Affinity DataEC50:  115nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50012906(CHEMBL3261323 | USRE46024, 10)
Affinity DataEC50:  767nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM237173(USRE46024, 11)
Affinity DataEC50:  1.20E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50012911(CHEMBL3261332 | USRE46024, 12)
Affinity DataEC50:  133nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50012907(CHEMBL3261336 | USRE46024, 13)
Affinity DataEC50:  92nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50012910(CHEMBL3261326 | USRE46024, 14)
Affinity DataEC50:  2.99E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50012917(CHEMBL3261327 | USRE46024, 15)
Affinity DataEC50:  601nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50012913(CHEMBL3261333 | USRE46024, 16)
Affinity DataEC50:  66nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50012903(CHEMBL3261328 | USRE46024, 17)
Affinity DataEC50:  2.04E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM237174(USRE46024, 18)
Affinity DataEC50:  9.18E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50012817(CHEMBL3261330 | USRE46024, 19)
Affinity DataEC50:  6.98E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM237175(USRE46024, 20)
Affinity DataEC50:  7.04E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM237176(USRE46024, 21)
Affinity DataEC50:  3.21E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50012908(CHEMBL3261334 | USRE46024, 22)
Affinity DataEC50:  136nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50290189((2E,4E)-3-Methyl-5-[(1S,2S)-4-methylene-2-(5,5,8,8...)
Affinity DataEC50:  169nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails Article

TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50290186((2E,4E)-3-Methyl-5-[(1R,2R)-1-methyl-2-(5,5,8,8-te...)
Affinity DataEC50:  7nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails Article

TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50290188((2E,4E)-3-Methyl-5-[(1S,2R)-1-methyl-2-(5,5,8,8-te...)
Affinity DataEC50:  62nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails Article

TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50290192(3-Methyl-5-[5-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Affinity DataEC50:  4nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails Article

TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50290190((2E,4E)-3-Methyl-5-[(1R,2S)-4-methylene-2-(5,5,8,8...)
Affinity DataEC50:  189nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails Article

TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataEC50:  28nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50290191(3-Methyl-5-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Affinity DataEC50:  53nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails Article

TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50290194((2E,4E)-3-Methyl-5-[(1S,2S)-2-(5,5,8,8-tetramethyl...)
Affinity DataEC50:  31nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails Article

TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50290193(3-Methyl-5-[2-(3,5,5,8,8-pentamethyl-5,6,7,8-tetra...)
Affinity DataEC50:  95nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails Article

TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50290187((2E,4E)-3-Methyl-5-[(1R,2S)-2-(5,5,8,8-tetramethyl...)
Affinity DataEC50:  8nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails Article

TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50290659((2E,4E)-3-Methyl-5-[1-(5,5,8,8-tetramethyl-5,6,7,8...)
Affinity DataEC50:  23nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails Article

TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50290660((2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7...)
Affinity DataEC50:  5nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails Article

TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataEC50:  33nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50290662((2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7...)
Affinity DataEC50:  2.52E+3nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails Article

TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50033079(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Affinity DataEC50:  409nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails Article

TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50403584(CHEMBL2111534)
Affinity DataEC50: >1.00E+3nMAssay Description:Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoid X receptor alpha using transactivation a...More data for this Ligand-Target Pair
In DepthDetails Article

TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50403583(CHEMBL2111535)
Affinity DataEC50: >1.00E+3nMAssay Description:Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoid X receptor alpha using transactivation a...More data for this Ligand-Target Pair
In DepthDetails Article

TargetRetinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50101444((E)-3-Methyl-5-[2-methyl-2-(5,5,8,8-tetramethyl-5,...)
Affinity DataEC50:  1.5nMAssay Description:Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoid X receptor alpha using transactivation a...More data for this Ligand-Target Pair
In DepthDetails Article

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