Affinity DataEC50: 160nMAssay Description:Inhibition of human alpha2 beta1 expressed in CHO cells assessed as reduction in cell adhesion to collagen type 1 incubated for 5 mins by DiOC6 dye b...More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Inhibition of human alpha2 beta1 expressed in CHO cells assessed as reduction in cell adhesion to collagen type 1 incubated for 5 mins by DiOC6 dye b...More data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at recombinant integrin alpha2 beta1 receptor (unknown origin) assessed as inhibition of interaction with biotinylated collagen t...More data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Displacement of FITC-labeled fibrinogen from alpha2beta3 in human plateletsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of alpha2beta1 integrin-mediated cell adhesion to type 1 collagen in human platelets incubated for 30 mins in presence of ADP by microplat...More data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity against integrin alpha2bbeta3 open form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Displacement of FITC-labeled fibrinogen from alpha2beta3 in human plateletsMore data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Displacement of FITC-labeled fibrinogen from alpha2beta3 in human plateletsMore data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Displacement of FITC-labeled fibrinogen from alpha2beta3 in human plateletsMore data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at alpha2beta1 integrin receptor (unknown origin) by cell-free ELISAMore data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Antagonist activity against integrin alpha2bbeta3 closed form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregatio...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at recombinant integrin alpha2 beta1 receptor (unknown origin) assessed as inhibition of interaction with biotinylated collagen t...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human alpha2 beta1 in human platelets assessed as reduction in platelet adhesion to collagen type 1 incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of alpha2beta1 integrin-mediated cell adhesion to type 1 collagen in human platelets incubated for 30 mins in presence of ADP by microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:Flat bottom microtiter plates (96-well) were coated with soluble type I collagen. Unoccupied protein binding sites on the wells were blocked with bov...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMpH: 7.4 T: 2°CAssay Description:Flat bottom microtiter plates (96-well) were coated with soluble type I collagen. Unoccupied protein binding sites on the wells were blocked with bov...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of alpha2beta1 integrin-mediated cell adhesion to type 1 collagen in human platelets incubated for 30 mins in presence of ADP by microplat...More data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Displacement of FITC-labeled fibrinogen from alpha2beta3 in human plateletsMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMpH: 7.4 T: 2°CAssay Description:Flat bottom microtiter plates (96-well) were coated with soluble type I collagen. Unoccupied protein binding sites on the wells were blocked with bov...More data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Antagonist activity against integrin alpha2bbeta3 open form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Antagonist activity at integrin alpha2beta3-mediated aggregation in ADP-stimulated human plateletsMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of alpha2beta1 integrin-mediated cell adhesion to type 1 collagen in human platelets incubated for 30 mins in presence of ADP by microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMpH: 7.4 T: 2°CAssay Description:Flat bottom microtiter plates (96-well) were coated with soluble type I collagen. Unoccupied protein binding sites on the wells were blocked with bov...More data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Antagonist activity against integrin alpha2bbeta3 open form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Antagonist activity against integrin alpha2bbeta3 closed form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregatio...More data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated plateletsMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Antagonist activity at recombinant integrin alpha2 beta1 receptor (unknown origin) assessed as inhibition of interaction with biotinylated collagen t...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMpH: 7.4 T: 2°CAssay Description:Flat bottom microtiter plates (96-well) were coated with soluble type I collagen. Unoccupied protein binding sites on the wells were blocked with bov...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMpH: 7.4 T: 2°CAssay Description:Flat bottom microtiter plates (96-well) were coated with soluble type I collagen. Unoccupied protein binding sites on the wells were blocked with bov...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Antagonist activity at recombinant integrin alpha2 beta1 receptor (unknown origin) assessed as inhibition of interaction with biotinylated collagen t...More data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Displacement of FITC-labeled fibrinogen from alpha2beta3 in human plateletsMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Antagonist activity at recombinant integrin alpha2 beta1 receptor (unknown origin) assessed as inhibition of interaction with biotinylated collagen t...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMpH: 7.4 T: 2°CAssay Description:Flat bottom microtiter plates (96-well) were coated with soluble type I collagen. Unoccupied protein binding sites on the wells were blocked with bov...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMpH: 7.4 T: 2°CAssay Description:Flat bottom microtiter plates (96-well) were coated with soluble type I collagen. Unoccupied protein binding sites on the wells were blocked with bov...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMpH: 7.4 T: 2°CAssay Description:Flat bottom microtiter plates (96-well) were coated with soluble type I collagen. Unoccupied protein binding sites on the wells were blocked with bov...More data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of alpha2beta1 integrin-mediated cell adhesion to type 1 collagen in human platelets incubated for 30 mins in presence of ADP by microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Flat bottom microtiter plates (96-well) were coated with soluble type I collagen. Unoccupied protein binding sites on the wells were blocked with bov...More data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Flat bottom microtiter plates (96-well) were coated with soluble type I collagen. Unoccupied protein binding sites on the wells were blocked with bov...More data for this Ligand-Target Pair
TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 96nMAssay Description:Antagonist activity against integrin alpha2bbeta3 in human platelet rich plasmaMore data for this Ligand-Target Pair
3D Structure (crystal)TargetIntegrin alpha-2/beta-3(Human)
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
A.V. Bogatsky Physico-Chemical Institute of The National Academy of Sciences of Ukraine
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Antagonist activity against integrin alpha2bbeta3 closed form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregatio...More data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:Antagonist activity at recombinant integrin alpha2 beta1 receptor (unknown origin) assessed as inhibition of interaction with biotinylated collagen t...More data for this Ligand-Target Pair
Affinity DataIC50: 102nMAssay Description:Flat bottom microtiter plates (96-well) were coated with soluble type I collagen. Unoccupied protein binding sites on the wells were blocked with bov...More data for this Ligand-Target Pair
Affinity DataIC50: 105nMpH: 7.4 T: 2°CAssay Description:Flat bottom microtiter plates (96-well) were coated with soluble type I collagen. Unoccupied protein binding sites on the wells were blocked with bov...More data for this Ligand-Target Pair
