Compile Data Set for Download or QSAR
Report error Found 25 for UniProtKB: P14916
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Jishou University

Curated by ChEMBL
LigandPNGBDBM50449754(CHEMBL4167553)
Affinity DataIC50: 43nMAssay Description:Inhibition of Helicobacter pylori ATCC 43504 urease assessed as reduction in ammonia production preincubated for 1.5 hrs under cell free condition by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221061(7-(4-Acetylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-...)
Affinity DataIC50: 1.22E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221056(7-(4-Acetylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-...)
Affinity DataIC50: 1.29E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221063(7-(4-(3,4,5-Trimethoxy piperazin-1-yl))-1-cyclopro...)
Affinity DataIC50: 2.08E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221066((S)-9-Fluoro-3,7-dihydro-N-hydroxy-3-methyl-10-(4-...)
Affinity DataIC50: 2.20E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221051(7-(4-Acetylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-...)
Affinity DataIC50: 2.22E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221050(N-acetyl ciprofloxacin)
Affinity DataIC50: 2.26E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221067((S)-9-Fluoro-3,7-dihydro-N,3-dimethyl-10-(4-methyl...)
Affinity DataIC50: 2.89E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221058(7-(4-(3,4,5-Trimetoxybenzoylpiperazin-1-yl))-1-cyc...)
Affinity DataIC50: 2.92E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221053(7-(4-(3,4,5-Trimethoxybenzoylpiperazin-1-yl)-1-cyc...)
Affinity DataIC50: 7.17E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221052(7-(4-Benzoylpiperazin-1-yl)-1-cyclopropyl-6-fluoro...)
Affinity DataIC50: 1.89E+4nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221054(7-(4-((4-((E)-3-(Phenylacryloyl)phenylcarbamoyl)me...)
Affinity DataIC50: 1.93E+4nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Jishou University

Curated by ChEMBL
LigandPNGBDBM50099857(acetohydroxamic acid | AHA | Acethydroxamsaeure | ...)
Affinity DataIC50: 4.25E+4nMpH: 7.4 T: 2°CAssay Description:Briefly, 50 mL broth cultures (2.0 × 10^8 CFU/mL) were centrifuged (5000g, 4°C)to collect the bacteria, and after washing twice with phosph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Jishou University

Curated by ChEMBL
LigandPNGBDBM236555(5-Methylpyrazine-2-carboxylic acid)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Briefly, 50 mL broth cultures (2.0 × 10^8 CFU/mL) were centrifuged (5000g, 4°C)to collect the bacteria, and after washing twice with phosph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Jishou University

Curated by ChEMBL
LigandPNGBDBM197303(SAMPL4, O2 | 4-Methylbenzoic acid)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Briefly, 50 mL broth cultures (2.0 × 10^8 CFU/mL) were centrifuged (5000g, 4°C)to collect the bacteria, and after washing twice with phosph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Jishou University

Curated by ChEMBL
LigandPNGBDBM10999(CHEMBL522 | Benzenemethanamine | phenylmethanamine...)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:Briefly, 50 mL broth cultures (2.0 × 10^8 CFU/mL) were centrifuged (5000g, 4°C)to collect the bacteria, and after washing twice with phosph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM50099857(acetohydroxamic acid | AHA | Acethydroxamsaeure | ...)
Affinity DataIC50: 1.20E+5nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221062(7-(4-Benzoylpiperazin-1-yl)-1-cyclopropyl-6-fluoro...)
Affinity DataIC50: 2.50E+5nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221060(7-(4-((4-((E)-3-(3,4,5-Trimetoxyphenylacryloyl)phe...)
Affinity DataIC50: 6.31E+5nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221068((S)-9-Fluoro-3,7-dihydro-3-methyl-10-(4-methylpipe...)
Affinity DataIC50: 7.72E+5nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221064(7-(4-((4-((E)-3-(Phenylacryloyl)phenylcarbamoyl)me...)
Affinity DataIC50: 8.12E+5nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221065(7-(4-((4-((E)-3-(3,4,5-Trimetoxyphenylacryloyl)phe...)
Affinity DataIC50: 9.12E+5nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221055(7-(4-((4-((E)-3-(3,4,5-Trimetoxyphenylacryloyl)phe...)
Affinity DataIC50: 9.49E+5nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221059(7-(4-((4-((E)-3-(Phenylacryloyl)phenylcarbamoyl)me...)
Affinity DataIC50: 2.41E+6nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrease subunit alpha(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Minia University

LigandPNGBDBM221057(7-(4-Benzoylpiperazin-1-yl)-1-cyclopropyl-6-fluoro...)
Affinity DataIC50: 2.50E+6nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed