Compile Data Set for Download or QSAR
Report error Found 105 for UniProtKB: P11541
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50241303(ethyl hydrogen (1-(3-(1-methyl-7-oxo-3-propyl-6,7-...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of phosphodiesterase 6 from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117721(3-Isobutyl-1-methyl-8-[5-(piperazin-1-ylmethanesul...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50130020(2-(2-Methyl-pyridin-4-ylmethyl)-1-oxo-8-(pyridin-2...)
Affinity DataIC50: 4.40nMAssay Description:Inhibitory activity against Phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117715(3-Isobutyl-1-methyl-8-[5-(4-methyl-piperazine-1-su...)
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50130025(7-(2-Methyl-pyridin-4-ylmethyl)-8-oxo-2-(pyrazin-2...)
Affinity DataIC50: 7.70nMAssay Description:Inhibitory activity against Phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50130021(7-(2-Methyl-pyridin-4-ylmethyl)-8-oxo-2-(pyridin-2...)
Affinity DataIC50: 8.60nMAssay Description:Inhibitory activity against Phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM235735(US9359371, 3)
Affinity DataIC50: 8.89nMpH: 7.5Assay Description:Method: The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (0.2 μg/mL) in Tris-HCl buffer of pH 7.5. 100 μ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50130027(8-Oxo-2-(pyridin-2-ylmethoxy)-7-pyridin-4-ylmethyl...)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against Phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117719(4-[3-(3-Isobutyl-1-methyl-2,6-dioxo-2,3,6,7-tetrah...)
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117711(8-{5-[4-(2-Hydroxy-ethyl)-piperazine-1-sulfonyl]-2...)
Affinity DataIC50: 15nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117724(3-(3-Isobutyl-1-methyl-2,6-dioxo-2,3,6,7-tetrahydr...)
Affinity DataIC50: 16nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117734(8-{5-[4-(2-Hydroxy-ethyl)-piperidine-1-sulfonyl]-2...)
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 20nMAssay Description:Inhibition of phosphodiesterase 6 from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50366818(CHEMBL1202833)
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against Phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50130028(7-(4-Amino-phenyl)-8-oxo-2-(pyridin-2-ylmethoxy)-5...)
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against Phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 25nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50100662(CHEMBL77971 | CHEMBL553371 | methyl 2-(4-aminophen...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against Phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against Phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117718(8-{5-[4-(2-Dimethylamino-ethyl)-piperazine-1-sulfo...)
Affinity DataIC50: 37nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50130019(8-Oxo-2-(pyridin-2-ylmethoxy)-7-pyridin-3-ylmethyl...)
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against Phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 40nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50130026(7-(2-Methyl-pyridin-4-ylmethyl)-8-oxo-2-(pyrimidin...)
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against Phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50130017(2-(2-Methyl-pyridin-4-ylmethyl)-1-oxo-8-(pyrimidin...)
Affinity DataIC50: 56nMAssay Description:Inhibitory activity against Phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM235755(US9359371, 38)
Affinity DataIC50: 58nMpH: 7.5Assay Description:Method: The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (0.2 μg/mL) in Tris-HCl buffer of pH 7.5. 100 μ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM235742(US9359371, 11)
Affinity DataIC50: 61nMpH: 7.5Assay Description:Method: The test compound or solvent was incubated at 25° C. for 15 min with enzyme solution (0.2 μg/mL) in Tris-HCl buffer of pH 7.5. 100 μ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50165810(5-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Affinity DataIC50: 63nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117736(8-{2-Ethoxy-5-[4-(2-hydroxy-ethyl)-piperazine-1-su...)
Affinity DataIC50: 68nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50130024(2-(2-Methyl-pyridin-4-ylmethyl)-1-oxo-8-(2-pyridin...)
Affinity DataIC50: 72nMAssay Description:Inhibitory activity against Phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117723(8-(2-Isobutoxy-phenyl)-3-isobutyl-1-methyl-3,7-dih...)
Affinity DataIC50: 73nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 74nMAssay Description:Inhibition of bovine retina PDE6 (Phosphodiesterase 6)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117732(3-Isobutyl-8-[2-isopropoxy-5-(4-methyl-piperazine-...)
Affinity DataIC50: 77nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117707(8-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 83nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117731(3-Isobutyl-1-methyl-8-(2-propoxy-phenyl)-3,7-dihyd...)
Affinity DataIC50: 87nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117729(3-Isobutyl-8-{5-[4-(2-methoxy-ethyl)-piperazine-1-...)
Affinity DataIC50: 91nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117701(8-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117705(8-[2-Isobutoxy-5-(4-methyl-piperazine-1-sulfonyl)-...)
Affinity DataIC50: 102nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50165805(4-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Affinity DataIC50: 110nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 140nMAssay Description:Inhibition of bovine retina PDE6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50304788(methyl 4-(3-chloro-4-methoxybenzylamino)-8-(2-hydr...)
Affinity DataIC50: 140nMAssay Description:Inhibition of bovine retina PDE6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50272569(CHEMBL4128481)
Affinity DataIC50: 142nMAssay Description:Inhibition of bovine retina PDE6A using 3',5'-[3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117716(8-{5-[4-(2-Dimethylamino-ethyl)-piperazine-1-sulfo...)
Affinity DataIC50: 146nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50166820(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 184nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117708(8-[2-Ethoxy-5-(piperazin-1-ylmethanesulfonyl)-phen...)
Affinity DataIC50: 203nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50166817(3-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phen...)
Affinity DataIC50: 204nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117717(3-Isobutyl-8-(2-isopropoxy-phenyl)-1-methyl-3,7-di...)
Affinity DataIC50: 214nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117704(3-Cyclopropylmethyl-8-[2-ethoxy-5-(4-methyl-pipera...)
Affinity DataIC50: 217nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117725(8-(2-Ethoxy-phenyl)-3-isobutyl-1-methyl-3,7-dihydr...)
Affinity DataIC50: 227nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50130018(8-Oxo-2-(pyridin-2-ylmethoxy)-7-pyridin-2-ylmethyl...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against Phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50117714(N-(2-Dimethylamino-ethyl)-N-ethyl-3-(3-isobutyl-1-...)
Affinity DataIC50: 242nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50166821(3-[2-Ethoxy-5-(4-isopropyl-piperazine-1-sulfonyl)-...)
Affinity DataIC50: 275nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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