Compile Data Set for Download or QSAR
Report error Found 106 of affinity data for UniProtKB/TrEMBL: P11344
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50044784(CHEBI:79090 | SB-202190 | US10865384, Compound SB2...)
Affinity DataIC50: 30nMAssay Description:Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50044784(CHEBI:79090 | SB-202190 | US10865384, Compound SB2...)
Affinity DataIC50: 30nMAssay Description:Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50045333(CHEBI:90705 | SB-203580)
Affinity DataIC50: 34nMAssay Description:Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50045333(CHEBI:90705 | SB-203580)
Affinity DataIC50: 34nMAssay Description:Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50230001(4-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)...)
Affinity DataIC50: 89nMAssay Description:Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50230001(4-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)...)
Affinity DataIC50: 89nMAssay Description:Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50193667(2,4,3',5'-tetrahydroxybibenzyl | CHEMBL221291)
Affinity DataIC50: 300nMAssay Description:Inhibition of tyrosinase in mouse B16 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50193667(2,4,3',5'-tetrahydroxybibenzyl | CHEMBL221291)
Affinity DataIC50: 300nMAssay Description:Inhibition of tyrosinase in mouse B16 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50237231(CHEMBL4063130)
Affinity DataIC50: 750nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50529600(CHEMBL4445400)
Affinity DataIC50: 800nMAssay Description:Inhibition of tyrosinase in mouse B16 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50529600(CHEMBL4445400)
Affinity DataIC50: 800nMAssay Description:Inhibition of tyrosinase in mouse B16 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50237232(CHEMBL516671)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50108046((oxyresveratrol)4-[(E)-2-(3,5-dihydroxyphenyl)viny...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50108046((oxyresveratrol)4-[(E)-2-(3,5-dihydroxyphenyl)viny...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50240041(1-phenyl-2-thiourea | N-Phenyl-thiourea | N-Phenyl...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of tyrosinase in alpha-MSH-induced mouse B16 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50251013(morachalcone A | 2,4,2',4'-tetrahydroxy-3'-prenylc...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50251013(morachalcone A | 2,4,2',4'-tetrahydroxy-3'-prenylc...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50529589(CHEMBL4239110)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50529589(CHEMBL4239110)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50520909(CHEMBL4461557)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of tyrosinase in mouse B16-F1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50237229(CHEMBL4083227)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50237230(CHEMBL4101226)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50203985(2,2',4,4'-tetrahydroxychalcone | 2,4,2',4'-tetrahy...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50203985(2,2',4,4'-tetrahydroxychalcone | 2,4,2',4'-tetrahy...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM175278((E)-2,3-bis(4-Hydroxyphenyl)acrylonitrile (21))
Affinity DataIC50: 5.06E+3nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50095997(3',4',7-trihydroxyisoflavone | CHEMBL13486)
Affinity DataIC50: 5.23E+3nMAssay Description:Inhibition of tyrosinase in mouse Melan-a cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50529588(Bisabolangelone)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in alpha-MSH induced melanin synthesisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50529588(Bisabolangelone)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in alpha-MSH induced melanin synthesisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618270(CHEMBL5436239)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of tyrosinase in mouse B16-F10 cells assessed as inhibition of melanin production measured after 72 hrsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM23926(5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol...)
Affinity DataIC50: 1.08E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50209568(7,8,4'-trihydroxyisoflavone | 7,8-dihydroxy-3-(4-h...)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of tyrosinase in mouse Melan-a cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM175269(Trans-4-Styryl-phenol (8))
Affinity DataIC50: 1.74E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of tyrosinase in mouse B16-F10 cells assessed as inhibition of melanin production measured after 72 hrsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50521808(CHEMBL4462424)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of tyrosinase in mouse B16F0 cells assessed as reduction in melanin production incubated for 24 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50296247(3-(3,4-Dihydroxyphenyl)-N-[2-(5-hydroxyindol-3-yl)...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50521808(CHEMBL4462424)
Affinity DataIC50: 3.01E+4nMAssay Description:Inhibition of tyrosinase in mouse B16F0 cells using L-DOPA as substrate by UV-Visible spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50219502(4-hydroxyphenyl beta-D-glucopyranoside | hydroquin...)
Affinity DataIC50: 3.03E+4nMAssay Description:Inhibition of tyrosinase in mouse Melan-a cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50520917(CHEMBL4450699)
Affinity DataIC50: 4.02E+4nMAssay Description:Inhibition of tyrosinase in mouse B16-F1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50296244(2,4-dihydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50520915(CHEMBL4544904)
Affinity DataIC50: 4.67E+4nMAssay Description:Inhibition of tyrosinase in mouse B16-F1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM175267(Trans-4-Styrylbenzonitrile (6))
Affinity DataIC50: 5.00E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM175271(Trans-1-fluoro-4-(4-methoxystyryl)benzene (10))
Affinity DataIC50: 5.00E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50342164(5-(3-Chlorobenzyloxy)benzene-1,3-diol | CHEMBL1766...)
Affinity DataIC50: 5.47E+4nMAssay Description:Inhibition of tyrosinase activity in alpha-MSH-stimulated mouse B16 cells using L-tyrosine as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM175272(Trans-2-Bromo-1-methoxy-4-styryl-benzene (11))
Affinity DataIC50: 5.62E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50618269(CHEMBL5434151)
Affinity DataIC50: 6.13E+4nMAssay Description:Inhibition of tyrosinase in mouse B16-F10 cells assessed as inhibition of melanin production measured after 72 hrsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50520911(CHEMBL4544938)
Affinity DataIC50: 6.52E+4nMAssay Description:Inhibition of tyrosinase in mouse B16-F1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50342165(5-(3,4-Dichlorobenzyloxy)benzene-1,3-diol | CHEMBL...)
Affinity DataIC50: 6.64E+4nMAssay Description:Inhibition of tyrosinase activity in alpha-MSH-stimulated mouse B16 cells using L-tyrosine as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM32212(cid_16054 | 1H-indol-5-ol)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50296245(3,4-Dihydroxy-N-[2-(5-hydroxyindol-3-yl)ethyl]benz...)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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