Compile Data Set for Download or QSAR
Report error Found 19 of affinity data for UniProtKB/TrEMBL: P05182
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183063((2R,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM31682(imidazole-dioxolane, 32)
Affinity DataIC50: 3.60E+3nMpH: 7.4Assay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183062(CHEMBL541899 | CHEMBL495072 | 1-((2-(4-chlorophene...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183058(1-(((2R,4S)-2-(4-chlorophenethyl)-4-methyl-1,3-dio...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183068(2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)m...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183064((2S,4S)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183069(1-(((2S,4R)-2-(4-chlorophenethyl)-4-methyl-1,3-dio...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM31652(imidazole-dioxolane, 3)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM31672(imidazole-dioxolane, 24)
Affinity DataIC50: 1.00E+5nMpH: 7.4Assay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM31669(imidazole-dioxolane, 21)
Affinity DataIC50: 1.00E+5nMpH: 7.4Assay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM31665(imidazole-dioxolane, 17)
Affinity DataIC50: 1.00E+5nMpH: 7.4Assay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM31664(imidazole-dioxolane, 16)
Affinity DataIC50: 1.00E+5nMpH: 7.4Assay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM31658(imidazole-dioxolane, 10)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM31657(imidazole-dioxolane, 9)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM31656(imidazole-dioxolane, 8)
Affinity DataIC50: 1.00E+5nMpH: 7.4 T: 2°CAssay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2009
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50027780(CHEMBL1908229)
Affinity DataKi:  1.00E+5nMAssay Description:Mechanism based inhibition of rabbit cytochrome P450 CYP2E1 measured by 7-EFC O-deethylation activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50027781(Diallylsulfone)
Affinity DataKi:  1.88E+5nMAssay Description:Mechanism based inhibition of rat cytochrome P450 CYP2E1 measured by P-nitrophenol (PNP) hydroxylase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50592756(CHEMBL5182450)
Affinity DataKi:  1.96E+5nMAssay Description:Inhibition of CYP2E1 in rat liver microsomes using chlorzoxazone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50027798(CHEMBL1908221)
Affinity DataKi:  1.00E+6nMAssay Description:Mechanism based inhibition of rabbit cytochrome P450 CYP2E1 measured by 7-EFC O-deethylation activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed