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Report error Found 3 of affinity data for UniProtKB/TrEMBL: P00962
TargetGlutamine--tRNA ligase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50614451(CHEMBL5291357)
Affinity DataKi:  280nMAssay Description:Binding affinity to Escherichia coli K12 glutaminyl-tRNA synthetase assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutamine--tRNA ligase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM18120([(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihyd...)
Affinity DataKi:  6.50E+5nM ΔG°:  -18.9kJ/molepH: 7.2 T: 2°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutamine--tRNA ligase(Escherichia coli (strain K12))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM18118((4S)-4-amino-6-({[(2R,3S,4R,5R)-5-(6-amino-9H-puri...)
Affinity DataKi:  2.80E+6nM ΔG°:  -15.2kJ/molepH: 7.2 T: 2°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed