TargetProto-oncogene tyrosine-protein kinase ROS/Sodium-dependent phosphate transport protein 2B(Human)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:Inhibition of SLC34A2-ROS1 (unknown origin) expressed in human HCC78 cells assessed as reduction in cell viabilityMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human NaPi2b transfected in human KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human NaPi2bMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human NaPi2b transfected in human KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human NaPi2b stably expressed in CHO-K1 cells assessed as reduction in H2[33P]O4 uptake incubated for 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human NaPi2b transfected in human KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of human NaPi2b expressed in KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of human NaPi2bMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of human NaPi2b stably expressed in CHO-K1 cells assessed as reduction in H2[33P]O4 uptake incubated for 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of human NaPi2bMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of human NaPi2bMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human NaPi2b expressed in KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human NaPi2bMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of human NaPi2b transfected in human KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of human NaPi2bMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of human NaPi2bMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase ROS/Sodium-dependent phosphate transport protein 2B(Human)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of SLC34A2-ROS1 (unknown origin) expressed in human HCC78 cells assessed as reduction in cell viabilityMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of human NaPi2b transfected in human KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of human NaPi2b transfected in human KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of human NaPi2b expressed in KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of human NaPi2b transfected in human KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of human NaPi2b expressed in CHO-K1 cells assessed as reduction in [33P] uptake preincubated with compound for 30 mins followed by [33P]O4...More data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of human NaPi2b stably expressed in CHO-K1 cells assessed as reduction in H2[33P]O4 uptake incubated for 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of human NaPi2b expressed in CHO-K1 cells assessed as reduction in [33P] uptake preincubated with compound for 30 mins followed by [33P]O4...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of human NaPi2bMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of human NaPi2b expressed in KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibition of human NaPi2b expressed in KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibition of human NaPi2bMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human NaPi2b transfected in human KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human NaPi2b transfected in human KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human NaPi2b expressed in KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human NaPi2b transfected in human KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human NaPi2b expressed in KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human NaPi2b transfected in human KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human NaPi2b transfected in human KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 103nMAssay Description:Inhibition of human NaPi2b transfected in human KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 107nMAssay Description:Inhibition of human NaPi2b stably expressed in CHO-K1 cells assessed as reduction in H2[33P]O4 uptake incubated for 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Inhibition of human NaPi2bMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of human NaPi2b transfected in human KJMGER8 cells assessed as reduction in H2[33P]O4 uptake incubated for 60 mins by TopCount scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of human NaPi2a (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 141nMAssay Description:Inhibition of human NaPi2b stably expressed in CHO-K1 cells assessed as reduction in H2[33P]O4 uptake incubated for 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataIC50: 147nMAssay Description:Inhibition of human NaPi2b stably expressed in CHO-K1 cells assessed as reduction in H2[33P]O4 uptake incubated for 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human NaPi2b expressed in HEK293 cells coexpressing tetracyclin assessed as reduction in uptake of 33P-radiolabeled Pi incubated for 20...More data for this Ligand-Target Pair
Affinity DataIC50: 161nMAssay Description:Inhibition of human NaPi2b stably expressed in CHO-K1 cells assessed as reduction in H2[33P]O4 uptake incubated for 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataIC50: 162nMAssay Description:Inhibition of human NaPi2b stably expressed in CHO-K1 cells assessed as reduction in H2[33P]O4 uptake incubated for 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataIC50: 166nMAssay Description:Inhibition of human NaPi2b expressed in CHO-K1 cells assessed as reduction in [33P] uptake preincubated with compound for 30 mins followed by [33P]O4...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of human NaPi2bMore data for this Ligand-Target Pair
Affinity DataIC50: 179nMAssay Description:Inhibition of human NaPi2bMore data for this Ligand-Target Pair
Affinity DataIC50: 192nMAssay Description:Inhibition of human NaPi2b stably expressed in CHO-K1 cells assessed as reduction in H2[33P]O4 uptake incubated for 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
Affinity DataIC50: 201nMAssay Description:Inhibition of human NaPi2b stably expressed in CHO-K1 cells assessed as reduction in H2[33P]O4 uptake incubated for 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
