Compile Data Set for Download or QSAR
Report error Found 1348 of affinity data for UniProtKB/TrEMBL: O76083
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711677(US12187729, Example 28)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711680(US12187729, Example 31)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711694(US12187729, Example 45)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711696(US12187729, Example 47)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711695(US12187729, Example 46)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711678(US12187729, Example 29)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711697(US12187729, Example 48)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711464(US12187729, Example 1)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711670(US12187729, Example 21)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711682(US12187729, Example 33)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711676(US12187729, Example 27)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50034641(CHEMBL3360415)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PDE9A2 catalytic domain (unknown origin) using [3H]-cGMP/[3H]-cAMP as substrate after 15 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM317140(US9617269, Compound WYQ-90-D)
Affinity DataIC50: 0.600nMAssay Description:Inhibition activities of all the N-substituted pyrazolo [3,4-d] pyrimidine ketone compounds according to the present invention to the phosphodiestera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50034641(CHEMBL3360415)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50034641(CHEMBL3360415)
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]-cGMP from PDE9A2 (unknown origin) incubated for 15 mins by liquid scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711668(US12187729, Example 19)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711681(US12187729, Example 32)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711685(US12187729, Example 36)
Affinity DataIC50: 0.700nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50300099(6-benzyl-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50397844(CHEMBL2179099)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50397850(CHEMBL2179093)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM317136(US9617269, Compound WYQ-87-D | US9617269, Compound...)
Affinity DataIC50: 1nMAssay Description:Inhibition activities of all the N-substituted pyrazolo [3,4-d] pyrimidine ketone compounds according to the present invention to the phosphodiestera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711683(US12187729, Example 34)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711684(US12187729, Example 35)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711686(US12187729, Example 37)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711688(US12187729, Example 39)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM711691(US12187729, Example 42)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50034645(CHEMBL3360419)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PDE9A2 catalytic domain (unknown origin) using [3H]-cGMP/[3H]-cAMP as substrate after 15 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50034648(CHEMBL3360421)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PDE9A2 catalytic domain (unknown origin) using [3H]-cGMP/[3H]-cAMP as substrate after 15 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM131008(US8829000, 70)
Affinity DataIC50: 1.20nMT: 2°CAssay Description:To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50397845(CHEMBL2177125)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50397848(CHEMBL2179096)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50300113(1-cyclopentyl-6-[(3S,4S)-4-methyl-1-(quinoxalin-6-...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50300113(1-cyclopentyl-6-[(3S,4S)-4-methyl-1-(quinoxalin-6-...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50543967(CHEMBL4638644)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50300112(trans-1-cyclopentyl-6-(4-methyl-1-(quinoxalin-6-yl...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50300112(trans-1-cyclopentyl-6-(4-methyl-1-(quinoxalin-6-yl...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM111911(US8623901, 239)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The PDE9A2 enzymatic activity assay was run as scintillation proximity assay (SPA), in general according to the protocol of the manufacturer (GE Heal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM131013(US8829000, 185)
Affinity DataIC50: 2nMT: 2°CAssay Description:To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM131014(US8829000, 187)
Affinity DataIC50: 2nMT: 2°CAssay Description:To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50543966(CHEMBL4642683)
Affinity DataIC50: 2nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM712667(US12195469, Example 23)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50300099(6-benzyl-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50300099(6-benzyl-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50543965(CHEMBL4640285)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50462275(CHEMBL4249954)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant GST-tagged human PDE9A2 expressed in insect cells using cGMP as substrate after 1 hr by IMAP TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM111910(US8623901, 234)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:The PDE9A2 enzymatic activity assay was run as scintillation proximity assay (SPA), in general according to the protocol of the manufacturer (GE Heal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM131010(US8829000, 85)
Affinity DataIC50: 3nMT: 2°CAssay Description:To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM131012(US8829000, 180)
Affinity DataIC50: 3nMT: 2°CAssay Description:To 150 uL of buffer B (70 mmol/L Tris-HCl, pH7.5, 16.7 mmol/L MgCl2, 33.3 nmol/L [3H]-cGMP) solution containing [3H]-cGMP (specific activity=244.2 GB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
Go to US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50034642(CHEMBL3360416)
Affinity DataIC50: 3nMAssay Description:Inhibition of PDE9A2 catalytic domain (unknown origin) using [3H]-cGMP/[3H]-cAMP as substrate after 15 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2016
Entry Details Article
PubMed
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