TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Human)
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: 76nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 60nMAssay Description:Positive allosteric modulation of human recombinant alpha4beta1delta GABAA receptor expressed in delta-HEK cells assessed as potentiation of GABA-ind...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 140nMAssay Description:Positive allosteric modulation of human recombinant alpha4beta1delta GABAA receptor expressed in delta-HEK cells assessed as potentiation of GABA-ind...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 1.92E+3nMAssay Description:Positive allosteric modulation of human recombinant alpha4beta1delta GABAA receptor expressed in delta-HEK cells assessed as potentiation of GABA-ind...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 1.10E+3nMAssay Description:Positive allosteric modulation of human recombinant alpha4beta1delta GABAA receptor expressed in delta-HEK cells assessed as potentiation of GABA-ind...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Positive allosteric modulation of human recombinant alpha4beta1delta GABAA receptor expressed in delta-HEK cells assessed as potentiation of GABA-ind...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 980nMAssay Description:Positive allosteric modulation of human recombinant alpha4beta1delta GABAA receptor expressed in delta-HEK cells assessed as potentiation of GABA-ind...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Human)
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: 192nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Human)
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: 2.05E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Human)
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: 1.60E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Human)
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: 1.36E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Human)
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Human)
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: 240nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Human)
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: 1.24E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Human)
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: 299nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Human)
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: 577nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Human)
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: 744nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
Affinity DataEC50: 163nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta2delta (unknown origin)More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Human)
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataEC50: 2.01E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 182nMAssay Description:Antagonist activity at human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 245nMAssay Description:Antagonist activity at recombinant human alpha1beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.02E+3nMAssay Description:Antagonist activity at recombinant human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.02E+3nMAssay Description:Antagonist activity at recombinant human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Antagonist activity at human alpha1beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 6.76E+3nMAssay Description:Antagonist activity at recombinant human alpha1beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.32E+4nMAssay Description:Antagonist activity at human alpha1beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 88nMAssay Description:Antagonist activity at recombinant human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 195nMAssay Description:Antagonist activity at human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 1.03E+3nMAssay Description:Antagonist activity at recombinant human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-1/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 1.28E+3nMAssay Description:Antagonist activity at human alpha4beta1delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 4.95E+3nMAssay Description:Antagonist activity at human alpha1beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 6.68E+3nMAssay Description:Antagonist activity at recombinant human alpha1beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 1.32E+4nMAssay Description:Antagonist activity at human alpha1beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/delta(Human)
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 6.02E+4nMAssay Description:Antagonist activity at recombinant human alpha1beta2delta GABAA receptor expressed in HEK293 Flp-In cells by FMP assayMore data for this Ligand-Target Pair
