| Details for Substrate
Dual specificity mitogen-activated protein kinase kinase 1 without Explicit Binding Affinity Data |
| Binding Enzyme 1: | RAF proto-oncogene serine/threonine-protein kinase [305-648] |
| Binding Enzyme 2: | Serine/threonine-protein kinase B-raf [409-765] |
| Binding Enzyme 3: | Serine/threonine-protein kinase B-raf [410-766,V600E] |
| Synonyms: |
ERK activator kinase 1
|
Mitogen-activated protein kinase 1 (MEK1)
|
MAPK/ERK kinase 1 (MEK1)
|
Dual specificity mitogen-activated protein kinase kinase 1 (MEK)
|
MEK-1
|
MAP kinase kinase 1
|
MAPK/ERK kinase 1
|
Dual specificity mitogen-activated protein kinase (MEK)
|
Dual specificity mitogen-activated protein kinase kinase MEK1/2
|
Dual specificity mitogen-activated protein kinase kinase 1 (MEK1)
|
MP2K1_HUMAN
|
MAP2K1
|
MEK1
|
PRKMK1
|
VHL-MAP2K1/MAP2K2
|
Dual specificity mitogen-activated protein kinase kinase 1/Mitogen-activated protein kinase 1/RAF proto-oncogene serine/threonine-protein kinase
|
| Type: | Other Protein Type |
| Topology: | Linear |
| Mol. Mass.: | 43439.03 Dalton |
| Organism: | Human |
| Description: | Full-length human MEK-1 was generated by PCR and purified as a fusion protein from Escherichia coli lysates. |
| Residue: | 393 |
| Sequence: | MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV |
| |