| Assay Method Information | |
| | ChEMBL_1784706 (CHEMBL4256223) |
| Description: | Inhibition of ATR in human U2OS cells harboring ER-LBD fused TopBPI activation domain (978 to 1286 residues) assessed as reduction in 4-OHT-mediated nuclear translocation of TopBPI fragment by measuring gammaH2AX level after 24 hrs by Alexa Fluor 488 staining based fluorescence assay |
| Affinity data for this assay | |
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