| Assay Method Information | |
| | ChEMBL_1760792 (CHEMBL4195800) |
| Description: | Antagonist activity at prolink-tagged TrkB in human U2OS cells assessed as inhibition of BDNF-induced receptor phosphorylation by measuring reduction in EA-tagged SH2 protein recruitment preincubated for 30 mins followed by BDNF stimulation measured after 2 hrs by PathHunter enzyme complementation assay |
| Affinity data for this assay | |
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