Assay Method Information

Assay Name:  ChEMBL_1849192 (CHEMBL4349733)
Description:  Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation by measuring reduction in EA-tagged SH2 protein recruitment preincubated for 30 mins followed by NGF addition and measured by chemiluminescence method
Affinity data for this assay
 

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