Assay Method Information | |
| ChEMBL_1849192 (CHEMBL4349733) |
Description: | Antagonist activity at prolink-tagged full length human TrkA expressed in U2OS cells assessed as inhibition of NGF-induced receptor phosphorylation by measuring reduction in EA-tagged SH2 protein recruitment preincubated for 30 mins followed by NGF addition and measured by chemiluminescence method |
Affinity data for this assay | |
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