Assay Method Information

Assay Name:  ChEMBL_1770197 (CHEMBL4222309)
Description:  Inhibition of recombinant human His6-SUMO tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) using oligonucleosome as substrate pretreated for 15 mins followed by substrate addition measured after 60 mins in presence of [3H]SAM by liquid scintillation counting method
Affinity data for this assay
 

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