Reaction Details  Report a problem with these data
Cell Reactant:
Purine nucleoside phosphorylase
Syringe Reactant:
BDBM82018
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
2013-03-18
ΔG°:
-7.42±0.1 (kcal/mole)
pH:
7.4000±0.0000
Temperature:
298.1500±0.0000 (K)
Citation
 Edwards, AA; Mason, JM; Clinch, K; Tyler, PC; Evans, GB; Schramm, VL Altered enthalpy-entropy compensation in picomolar transition state analogues of human purine nucleoside phosphorylase. Biochemistry 48:5226-38 (2009) [PubMed]  Article 
Cell React
Name:
Purine nucleoside phosphorylase
Synonyms:
Inosine phosphorylase | Inosine-guanosine phosphorylase | Purine nucleoside phosphorylase (PNPase) | PNPH_HUMAN | PNP | NP
Type:
Enzyme
Mol. Mass.:
32119.53
Organism:
Human
Description:
n/a
Residue:
289
Sequence:
MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS
  
Syringe React
Name:
BDBM82018
Synonyms:
CAS_790 | CHEMBL1427 | NSC_790 | Hypoxanthine
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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