Reaction Details 
Report a problem with these data
Report a problem with these dataCell Reactant:
Phosphoehtnaolamine Methyltransferases 1 (PMT1)
Syringe Reactant:
BDBM28422
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
2012-09-18
ΔG°:
-6.22±0.24 (kcal/mole)
pH:
7.5000±0.0000
Temperature:
277.1500±0.0000 (K)
ΔH° :
-12.51±0.24 (kJ/mole)
ΔS° :
-0.02±0 (kJ/mole-K)
Citation
Lee, SG; Haakenson, W; McCarter, JP; Williams, DJ; Hresko, MC; Jez, JM Thermodynamic evaluation of ligand binding in the plant-like phosphoethanolamine methyltransferases of the parasitic nematode Haemonchus contortus. J Biol Chem 286:38060-8 (2011) [PubMed] Article More Info.:
Cell React
Name:
Phosphoethanolamine N-methyltransferase 1
Synonyms:
Phosphoehtnaolamine Methyltransferases 1 (PMT1)
Type:
Enzyme
Mol. Mass.:
53531.36
Organism:
Caenorhabditis elegans
Description:
Q86NB3
Residue:
475
Sequence:
MSTDQQSSVEDQTVAMVNVRRANFKSFWDKYSDKPDTNSMMLNHSAEELESSDRADILASLPLLHNKDVVDIGAGIGRFTTVLAETARWVLSTDFIDSFIKKNQERNAHLGNINYQVGDAVGLKMESNSVDLVFTNWLMMYLSDEETVEFIFNCMRWLRSHGIVHLRESCSEPSTGRSKAKSMHDTANANPTHYRFSSLYINLLRAIRYRDVDNKLWRFNVQWSCSVPTYIKRSNNWRQVHWLAEKVPAEDGAKGTSFNELVELIKNTWQNEQEAWDAKLDDEKYVWTDKVFSSALTSLPSNSTFFLYTPRTVSPYCHINAHTLAETFNANVWNTEIIPEYYRTSLTKSNNLKDQRVRFGWNQSLTDSVTYWQQKDALFDVFVATEFLSTVDDETIRQLPNVMSDGAKFITLEPVDEVNEAEMKQRIQELGYTLKSFTDVTDQCIEAQEQYFKDHEQLRDEKVIRKNWVLLELTH
Syringe React
Name:
BDBM28422
Synonyms:
(2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(methyl)sulfanylium)butanoate | [14COOH]AdoMet | AdoMet | S-Adenosylmethionine | S-adenosyl-L-[carboxy-14C]methionine
Type:
radiolabeled substrate
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
