Reaction Details  Report a problem with these data
Cell Reactant:
Alpha-fucosidase
Syringe Reactant:
BDBM50065258
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
2012-02-14
ΔG°:
-10.02±0 (kcal/mole)
pH:
6.5000±0.0000
Temperature:
37.0000±0.0000 (K)
ΔH° :
-15.62±0.1 (kJ/mole)
ΔS° :
0.02±0 (kJ/mole-K)
Citation
 Lammerts van Bueren, A; Popat, SD; Lin, CH; Davies, GJ Structural and thermodynamic analyses of α-L-fucosidase inhibitors. Chembiochem 11:1971-4 (2010) [PubMed]  Article 
Cell React
Name:
Alpha-fucosidase-like protein
Synonyms:
Alpha-fucosidase
Type:
Protein
Mol. Mass.:
49785.16
Organism:
Bacteroides thetaiotaomicron
Description:
Q8ABG8
Residue:
461
Sequence:
MKHIAFLSVKWMSVGLGMLSLLLSVASCGDKEYGDAMNEAQLMNDIEVNVGSSLPLAVGMDFVLDYKPVPENVTNPEITLTSSDENVVSVSQDGRVTAKMIGKAYINLSQSTAFETLKTIEVQVMPVATAIELENVELFEGTNKKVIVNVTPSDGYNVFDWKSDNEEVATVADDGTITGKKPGTANISVSSQDGSQLTATAVVTVKEVIPIDKITLSEPGYDMMIGDKTLINCLLEPIDASVGLLSWSTTNDRVATVDADGLVTAVGAGEAEIIAQDPLSGLSASIAVKVVGEGVVSLSLSYVRNQDELKALGWGFGQTPASVNFDAEGMTVNMSLQSNSKYRADLKMASNDRPVVLNIGTYRYLAFRMDVPGNGSLKLDTNKGDYGNNPTGVLAEDSQVIYYDLQAKPYFPTDAPSDKLTTFQLKIADVTVQPYSYKVYWVRTFKTLEDLKVYVEKENNK
  
Syringe React
Name:
BDBM50065258
Synonyms:
CHEMBL314772 | (2S,3R,4S,5R)-2-methylpiperidine-3,4,5-triol | Fucosidase Inhibitor, 3 | (2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: