Reaction Details  Report a problem with these data
Cell Reactant:
Pantothenate synthetase
Syringe Reactant:
BDBM84862
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
2012-02-14
pH:
7.6000±0.0000
Temperature:
298.1500±0.0000 (K)
ΔH° :
-22.44±0.1 (kJ/mole)
Citation
 Scott, DE; Dawes, GJ; Ando, M; Abell, C; Ciulli, A A fragment-based approach to probing adenosine recognition sites by using dynamic combinatorial chemistry. Chembiochem 10:2772-9 (2009) [PubMed]  Article 
Cell React
Name:
Pantothenate synthetase
Synonyms:
PANC_MYCTU | panC | Chain A, Crystal Structure Of A Pantothenate Synthetase, Apo Enzyme In C2 Space Group | Pantothenate synthetase
Type:
n/a
Mol. Mass.:
32675.10
Organism:
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Description:
ChEMBL_102878
Residue:
309
Sequence:
MTIPAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLALVRAAKRVPGSVVVVSIFVNPMQFGAGEDLDAYPRTPDDDLAQLRAEGVEIAFTPTTAAMYPDGLRTTVQPGPLAAELEGGPRPTHFAGVLTVVLKLLQIVRPDRVFFGEKDYQQLVLIRQLVADFNLDVAVVGVPTVREADGLAMSSRNRYLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLDAAPGVAVDYLELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIGTFAGTDRPDGYRAILESHWRN
  
Syringe React
Name:
BDBM84862
Synonyms:
5'-Deoxy-5'-thiodenosine scaffold, 6
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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