Cell Reactant:

Syringe Reactant:

Meas. Tech.:

ITC

Entry Date.:

2000-12-19

ΔG°:

-6.84±n/a (kcal/mole)

pH:

7.0000±n/a

Log₁₀Kb:

0

Temperature:

298.1500±n/a (K)

ΔH° :

-13.46±n/a (kJ/mole)

ΔH_obs :

-13.46±n/a (kJ/mole)

ΔS° :

-0.02±n/a (kJ/mole-K)

Comments:

high affinity site

Citation

 Cowan, JA; Ohyama, T; Wang, D; Natarajan, K Recognition of a cognate RNA aptamer by neomycin B: quantitative evaluation of hydrogen bonding and electrostatic interactions. Nucleic Acids Res 28:2935-42 (2000) [PubMed]  Article

More Info.:

Get all data from this article,  ITC RUN data,  Solution Info

Source:

in vitro transcription using T7 RNA polymerase

Prep. Method:

purified using PAGE and electroeluted from the gel

Name:

RNA(23-mer)

Synonyms:

RNA 23mer

Type:

RNA

Mol. Mass.:

1388.55

Organism:

n/a

Description:

n/a

Residue:

19

Sequence:

GGCCGGGCGAGAAGAGGCC

 

Source:

Sigma (St. Louis, MO)

Name:

BDBM19

Synonyms:

KDR Kinase Inhibitor, 3 | Neomycin | (2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(2R,3S,4R,5S)-5-{[(1R,2R,3S,5R,6S)-3,5-diamino-2-{[(2R,3R,4R,5S,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-6-hydroxycyclohexyl]oxy}-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}oxane-3,4-diol | Neomycin B

Type:

Small organic molecule

Emp. Form.:

TBD

Mol. Mass.:

TBD

SMILES:

TBD

Structure:

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