Reaction Details  Report a problem with these data
Cell Reactant:
Flavin reductase (NADPH)
Syringe Reactant:
BDBM50061625
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
2023-10-06
ΔG°:
-8.01±0.07 (kcal/mole)
Temperature:
298.1500±0.0000 (K)
ΔH° :
-4.5±0.07 (kJ/mole)
ΔS° :
0.01±0 (kJ/mole-K)
Citation
 Ryu, K; Kim, M; Griesinger, C; Lee, D Method of increasing platelet counts of a subject US Patent  US11744839 Publication Date 9/5/2023 
Cell React
Name:
Flavin reductase (NADPH)
Synonyms:
BLVRB_HUMAN | BLVRB | FLR | 1.3.1.24 | 1.5.1.30 | BVR-B | Biliverdin reductase B | Biliverdin-IX beta-reductase
Type:
PROTEIN
Mol. Mass.:
22123.63
Organism:
Human
Description:
ChEMBL_100283
Residue:
206
Sequence:
MAVKKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGDVLQAADVDKTVAGQDAVIVLLGTRNDLSPTTVMSEGARNIVAAMKAHGVDKVVACTSAFLLWDPTKVPPRLQAVTDDHIRMHKVLRESGLKYVAVMPPHIGDQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTDEYDGHSTYPSHQYQ
  
Syringe React
Name:
BDBM50061625
Synonyms:
4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl]benzoic acid | Am 80 | Tamibarotene | retinobenzoic acid | CHEMBL25202 | US9963439, AM80 | US11744839, Compound of formula 3
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: