Reaction Details  Report a problem with these data
Cell Reactant:
Transthyretin
Syringe Reactant:
BDBM13066
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
2022-08-28
ΔG°:
-8.8±0.6 (kcal/mole)
pH:
7.5000±0.0000
Temperature:
298.1500±0.0000 (K)
ΔH° :
-4.69±0.43 (kJ/mole)
ΔS° :
0.01±0 (kJ/mole-K)
Citation
 Graef, IA; Alhamadsheh, MM Identification of stabilizers of multimeric proteins US Patent  US11337935 Publication Date 5/24/2022 
Cell React
Name:
Transthyretin
Synonyms:
Transthyretin (TTR) | ATTR | Prealbumin | TBPA | TTHY_HUMAN | TTR | PALB
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Human
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
  
Syringe React
Name:
BDBM13066
Synonyms:
{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid | CHEMBL139 | 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid | Diclofenac | US11337935, Compound Diclofenac | US11478464, Compound Diclofenac | US11786535, Compound Diclofenac
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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