Compile Data Set for Download or QSAR
Report error Found 245 Enz. Inhib. hit(s) with all data for entry = 3293
TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396701(US9981944, Example 46 | 6-(6'-chloro-[2,2'-bipyrid...)
Affinity DataIC50: 0.400nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396672(US9981944, Example 18 | 6-(6'-(trifluoromethyl)-[2...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396673(US9981944, Example 19 | 6-(5'-fluoro-6'-methyl-[2,...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396683(US9981944, Example 29 | 6-(6'-(difluoromethyl)-[2,...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396687(US9981944, Example 33 | 6-(6'-methoxy-[2,2'-bipyri...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396689(US9981944, Example 35 | 6-(6'-cyclopropyl-[2,2'-bi...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396730(US9981944, Example 76 | N-(6-(6'-methyl-[2,2'-bipy...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396736(US9981944, Example 82 | 6-(5-fluoro-6'-methyl-[2,2...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396738(US9981944, Example 84 | 6-(6'-(difluoromethyl)-5-f...)
Affinity DataIC50: 1nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396726(US9981944, Example 72 | methyl-6-(6'-methyl-[2,2'-...)
Affinity DataIC50: 2nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396740(US9981944, Example 85 | 6-(5,5'-difluoro-6'-methyl...)
Affinity DataIC50: 2nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396753(US9981944, Example 98 | 6-(5-amino-6'-methyl-[2,2'...)
Affinity DataIC50: 2nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396764(US9981944, Example 109 | 6-(6'-(difluoromethyl)-[2...)
Affinity DataIC50: 2nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396765(US9981944, Example 110 | 6-(5'-fluoro-6'-methyl-[2...)
Affinity DataIC50: 2nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396766(US9981944, Example 111 | 6-(6'-isopropyl-[2,2'-bip...)
Affinity DataIC50: 2nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396772(US9981944, Example 117 | 5-(5'-fluoro-6'-methyl-[2...)
Affinity DataIC50: 2nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396702(US9981944, Example 47 | 6-(6'-methyl-[2,2'-bipyrid...)
Affinity DataIC50: 3nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396760(US9981944, Example 105 | 6-(6'-(difluoromethyl)-[2...)
Affinity DataIC50: 3nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396770(US9981944, Example 115 | 5-(6'-(difluoromethyl)-[2...)
Affinity DataIC50: 3nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396692(US9981944, Example 37 | 6-(6'-fluoro-[2,2'-bipyrid...)
Affinity DataIC50: 4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396722(US9981944, Example 67 | 6-(6'-methyl-[2,2'-bipyrid...)
Affinity DataIC50: 4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396723(US9981944, Example 68 | N-(2,2-difluoroethyl)-6-(6...)
Affinity DataIC50: 4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396725(US9981944, Example 70 | N-(2-methoxyethyl)-6-(6'-m...)
Affinity DataIC50: 4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396731(US9981944, Example 77 | N-(6-(5'-fluoro-6'-methyl-...)
Affinity DataIC50: 4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396754(US9981944, Example 99 | 6-(5-amino-6'-methyl-[2,2'...)
Affinity DataIC50: 4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396758(US9981944, Example 103 | 6-(5'-fluoro-6'-methyl-[2...)
Affinity DataIC50: 4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396761(US9981944, Example 106 | 6-(6'-cyclopropyl-[2,2'-b...)
Affinity DataIC50: 4nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396675(US9981944, Example 21 | 6-(5'-fluoro-[2,2'-bipyrid...)
Affinity DataIC50: 5nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396676(US9981944, Example 22 | 6-(4'-fluoro-[2,2'-bipyrid...)
Affinity DataIC50: 5nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396752(US9981944, Example 97 | 6-(5-acetamido-6'-methyl-[...)
Affinity DataIC50: 5nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396756(US9981944, Example 101 | 6-(4-amino-6'-methyl-[2,2...)
Affinity DataIC50: 5nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396793(US9981944, Example 138 | 5-(6'-methyl-[2,2'-bipyri...)
Affinity DataIC50: 5nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396694(US9981944, Example 39 | 6-([2,2'-bipyridin]-3- yl)...)
Affinity DataIC50: 6nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396775(US9981944, Example 120 | 5-(6'-methyl-[2,2'-bipyri...)
Affinity DataIC50: 6nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396724(US9981944, Example 69 | 6-(6'-methyl-[2,2'-bipyrid...)
Affinity DataIC50: 7nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396792(US9981944, Example 137 | 5-(5'-fluoro-6'-methyl-[2...)
Affinity DataIC50: 8nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396617(US9981944, Example 17 | 6-(6'-methoxy-[2,2'-bipyri...)
Affinity DataIC50: 9nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396682(US9981944, Example 28 | 6-(6'-(difluoromethyl)-[2,...)
Affinity DataIC50: 9nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396762(US9981944, Example 107 | 6-(6'-ethyl-[2,2'-bipyrid...)
Affinity DataIC50: 9nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396768(US9981944, Example 113 | 6-(6'-methyl-[2,2'-bipyri...)
Affinity DataIC50: 9nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396559(US9981944, Example 15 | 6-(5'-fluoro-6'-methyl-[2,...)
Affinity DataIC50: 10nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396404(US9981944, Example 14 | 6-(6'-(trifluoromethyl)-[2...)
Affinity DataIC50: 11nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396767(US9981944, Example 112 | 6-(5'-fluoro-6'-methyl-[2...)
Affinity DataIC50: 12nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396743(US9981944, Example 88 | 6-(6'-(difluoromethyl)-6-m...)
Affinity DataIC50: 13nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396771(US9981944, Example 116 | 5-(5'-fluoro-[2,2'-bipyri...)
Affinity DataIC50: 14nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396785(US9981944, Example 130 | ethyl 5-(5'-fluoro-6'-met...)
Affinity DataIC50: 14nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396742(US9981944, Example 87 | 6-(6,6'-dimethyl-[2,2'-bip...)
Affinity DataIC50: 15nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396791(US9981944, Example 136 | 5-(6'-(trifluoromethyl)-[...)
Affinity DataIC50: 15nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396686(US9981944, Example 32 | 6-(6'-isopropyl-[2,2'-bipy...)
Affinity DataIC50: 16nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396735(US9981944, Example 81 | 6-(5-fluoro-6'-methyl-[2,2...)
Affinity DataIC50: 16nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
Go to US Patent

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