Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 3199
TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM394120(US9975854, Compound 97 | (2R,6S,11R)-11-(((1-(2-hy...)
Affinity DataKi:  2.12nMAssay Description:μ-Opioid: Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
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TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM394118(US9975854, Compound 10 | (2R,6S,11R)-3,6-dimethyl-...)
Affinity DataKi:  301nMAssay Description:μ-Opioid: Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM394119(US9975854, Compound 55 | (2R,6S,11R)-11-(((1- (iso...)
Affinity DataKi: >2.00E+4nMAssay Description:μ-Opioid: Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
Go to US Patent