Compile Data Set for Download or QSAR
Report error Found 215 Enz. Inhib. hit(s) with all data for entry = 2896
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384287(US9932325, Example 1 | US10590114, No. 1 | US11111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384290(US9932325, Example 3)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384293(US9932325, Example 4)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384294(US9932325, Example 5 | US10590114, No. 5 | US11111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384297(US9932325, Example 7 | US10590114, No. 7 | US11111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384299(US9932325, Example 8 | US10590114, No. 8 | US11111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384304(US9932325, Example 9)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384307(US9932325, Example 11 | US11591316, Compound 11)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384308(US9932325, Example 12 | US11591316, Compound 12)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384309(US9932325, Example 13 | US10590114, No. 13 | US111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384310(US9932325, Example 218 | US9932325, Example 14 | U...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384311(US9932325, Example 15 | US10590114, No. 15 | US111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384312(US9932325, Example 16 | US10590114, No. 16 | US111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384314(US9932325, Example 17 | US10590114, No. 17 | US111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM196756(US9212173, 34 | US9932325, Example 18 | US10590114...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384317(US9932325, Example 19 | US10590114, No. 19 | US111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384318(US9932325, Example 20 | US10590114, No. 20 | US111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384321(US9932325, Example 21 | US10590114, No. 21 | US111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384323(US9932325, Example 23 | US9932325, Example 24 | US...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384323(US9932325, Example 23 | US9932325, Example 24 | US...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384323(US9932325, Example 23 | US9932325, Example 24 | US...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384328(US9932325, Example 25 | US10590114, No. 25 | US111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384330(US9932325, Example 27 | US9932325, Example 26 | US...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384330(US9932325, Example 27 | US9932325, Example 26 | US...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384334(US9932325, Example 29 | US9932325, Example 28 | US...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384334(US9932325, Example 29 | US9932325, Example 28 | US...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384343(US9932325, Example 32 | US10590114, No. 58 | US111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384346(US9932325, Example 33 | US10590114, No. 33 | US111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384347(US9932325, Example 34 | BDBM384370 | US10590114, N...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384349(US9932325, Example 35A | US10590114, No. 35A | US1...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384350(US9932325, Example 35B | US10590114, No. 35B | US1...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384352(US9932325, Example 37 | US10590114, No. 37 | US111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384355(BDBM384364 | US9932325, Example 38 | US10590114, N...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384356(US9932325, Example 39A | US10590114, No. 39A | US1...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM50448118(CHEMBL3122113 | US9932325, Example 80 | US10590114...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384358(US9932325, Example 41 | US10590114, No. 41 | US111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384359(US9932325, Example 42 | US10590114, No. 42 | US111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384360(US9932325, Example 43 | US10590114, No. 43 | US111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384361(US9932325, Example 44 | BDBM384401 | BDBM384388 | ...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM50448118(CHEMBL3122113 | US9932325, Example 80 | US10590114...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384363(BDBM384372 | US9932325, Example 46 | US10590114, N...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384355(BDBM384364 | US9932325, Example 38 | US10590114, N...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384365(US9932325, Example 50 | US10590114, No. 50 | US111...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384366(US9932325, Example 52B | US9932325, Example 52A | ...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384366(US9932325, Example 52B | US9932325, Example 52A | ...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384368(US9932325, Example 54B | US9932325, Example 54A | ...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384368(US9932325, Example 54B | US9932325, Example 54A | ...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384347(US9932325, Example 34 | BDBM384370 | US10590114, N...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
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TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384371(US9932325, Example 58 | US11111235, No. 58 | US115...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
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TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Denali Therapeutics

US Patent
LigandPNGBDBM384363(BDBM384372 | US9932325, Example 46 | US10590114, N...)
Affinity DataIC50: 30nMAssay Description:Materials: LRRK2 G2019S enzyme Substrate (LRRKtide) ATP TR-FRET dilution buffer pLRRKtide antibody 384-well assay plate DMSOEnzyme Reaction Condition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
Go to US Patent

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