Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 2765
TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380433(US9926299, 42 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380425(US9926299, 30 | 5-amino-1-(2-(N-methylacrylamido)e...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM303533(US10138229, Example 44 | US9926299, 31 | US1087585...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380427(US9926299, 32 | 5-amino-1-(2-(N-methylpropiolamido...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380428(US9926299, 33 | 5-amino-1-(2-(N-methylvinylsulfona...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380429(US9926299, 34 | 5-amino-1-(2-(2-chloro-N-methylace...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380430(US9926299, 35 | (E)-5-amino-1-(2-(4-(dimethylamino...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380431(US9926299, 37 | 1-(1-acryloylpiperidin-3-yl)-5-ami...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380432(US9926299, 41 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380424(US9926299, 29 | (E)-5-amino-1-(1-(4-(dimethylamino...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380434(US9926299, 43 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380435(US9926299, 44 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380436(US9926299, 45 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380437(US9926299, 46 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380438(US9926299, 47 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380439(US9926299, 48 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380440(US9926299, 49 | (R)-1-(1-acryloylpyrrolidin-3-yl)-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380071(US9926299, 24 | 1-(1-acryloylpiperidin-4-yl)-5-ami...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380015(US9926299, 2 | (R)-1-(1-acryloylpiperidin-3-yl)-5-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380018(US9926299, 6 | 1-(1-acryloylpiperidin-3-yl)-5-(eth...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380024(US9926299, 13 | 1-(1-acryloylpiperidin-3-yl)-5-(2-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380038(US9926299, 15 | 1-(1-acryloylpiperidin-3-yl)-5-(2-...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM303543(US10138229, Example 54 | US10266513, Example 127 |...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380053(US9926299, 20 | 5-amino-1-cyclohexyl-3-(4-phenoxyp...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380057(US9926299, 22 | 1-(1-acryloylpiperidin-3-yl)-5-ami...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM377832(1-[(3S)-1-acryloyl piperidin-3-yl]-5-amino-3-(4-ph...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380007(US9926299, 1 | 1-(1-acryloylpiperidin-3-yl)-5-(met...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380082(US9926299, 25 | 1-(1-acryloylpyrrolidin-3-yl)-5-am...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380418(US9926299, 25 (R-isomer))
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380419(US9926299, 25 (S-isomer))
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380420(US9926299, 26 | 5-amino-3-(4-phenoxyphenyl)-1-(1-p...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380421(US9926299, 27 | 5-amino-3-(4-phenoxyphenyl)-1-(1-(...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM295011(US10112922, Compound 1 | US9926299, 27 (R-isomer))
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM380423(US9926299, 28 | 5-amino-1-(1-(2-chloroacetyl)piper...)
Affinity DataIC50: 100nMAssay Description:Btk kinase activity was determined using a Homogeneous Time-Resolved Fluorescence (HTRF) methodology (Cisbio). Measurements were performed in a react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
Go to US Patent