Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 2100
LigandPNGBDBM352410(5′-(7-Ethyl-7H-imidazo[4,5-c]pyridazin-4-yl)...)
Affinity DataKi:  6.30nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352391(5-{2-Fluoro-5-[7-(propan-2-yl)-7H-imidazo[4,5-c]py...)
Affinity DataKi:  6.40nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352390(5-[5-(7-Ethyl-7H-imidazo[4,5-c]pyridazin-4-yl)-2-f...)
Affinity DataKi:  6.60nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352405(US9802945, 16)
Affinity DataKi:  6.70nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352398(US9802945, 9)
Affinity DataKi:  6.80nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352403(US9802945, 14)
Affinity DataKi:  7.5nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352401(2′-Fluoro-5′-[7-(propan-2-yl)-7H-imida...)
Affinity DataKi:  10.7nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352392(US9802945, 3)
Affinity DataKi:  12.8nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352407(US9802945, 18)
Affinity DataKi:  19.3nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352404(US9802945, 15)
Affinity DataKi:  20.3nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352400(5′-(7-Cyclopropyl-7H-imidazo[4,5-c]pyridazin...)
Affinity DataKi:  20.5nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352394(US9802945, 5)
Affinity DataKi:  21.7nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352393(US9802945, 4)
Affinity DataKi:  23.2nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352397(US9802945, 8)
Affinity DataKi:  29nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352396(US9802945, 7)
Affinity DataKi:  30.9nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352408(US9802945, 19)
Affinity DataKi:  51nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352406(US9802945, 17)
Affinity DataKi:  52.8nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352399(5-[5-(7-Cyclopropyl-7H-imidazo[4,5-c]pyridazin-4-y...)
Affinity DataKi:  54.7nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352402(5′-(7-Ethyl-7H-imidazo[4,5-c]pyridazin-4-yl)...)
Affinity DataKi:  71.6nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352411(5′-(7-Ethyl-7H-imidazo[4,5-c]pyridazin-4-yl)...)
Affinity DataKi:  81.2nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352395(US9802945, 6)
Affinity DataKi:  81.8nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352409(US9802945, 20)
Affinity DataKi:  224nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM352412(5′-(7-Ethyl-7H-imidazo[4,5-c]pyridazin-4-yl)...)
Affinity DataKi:  340nMAssay Description:The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent