Compile Data Set for Download or QSAR
Report error Found 135 Enz. Inhib. hit(s) with all data for entry = 2071
TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354293(1-(3-(tert-Butyl)-1-(4-(dimethylphosphoryl)phenyl)...)
Affinity DataIC50: 1nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
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US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM354311(1-(1-(3-((Dimethylphosphoryl)methyl)phenyl)-3-isop...)
Affinity DataIC50: 1nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM354293(1-(3-(tert-Butyl)-1-(4-(dimethylphosphoryl)phenyl)...)
Affinity DataIC50: 2nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354310(3-((4-((4-(3-(1-(3-((Dimethylphosphoryl)methyl)phe...)
Affinity DataIC50: 2nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354332(1-(3-(tert-Butyl)-1-(3-((dimethylphosphoryl)methyl...)
Affinity DataIC50: 2nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM354310(3-((4-((4-(3-(1-(3-((Dimethylphosphoryl)methyl)phe...)
Affinity DataIC50: 3nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
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US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354311(1-(1-(3-((Dimethylphosphoryl)methyl)phenyl)-3-isop...)
Affinity DataIC50: 3nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354324(1-(4-((2-((3-(2,5,8,11-Tetraoxatridecan-13-yloxy)-...)
Affinity DataIC50: 3nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM354324(1-(4-((2-((3-(2,5,8,11-Tetraoxatridecan-13-yloxy)-...)
Affinity DataIC50: 4nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
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US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354304(1-(3-(tert-Butyl)-1-(3-((dimethylphosphoryl)methyl...)
Affinity DataIC50: 5nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM354304(1-(3-(tert-Butyl)-1-(3-((dimethylphosphoryl)methyl...)
Affinity DataIC50: 5nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM354309(1-(1-(3-((Dimethylphosphoryl)methyl)phenyl)-3-isop...)
Affinity DataIC50: 5nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM354329(1-(4-((2-((3-cyano-5-(2-morpholinoethoxy)phenyl)am...)
Affinity DataIC50: 7nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354330(3-((4-((4-(3-(3-(tert-Butyl)-1-(3-((dimethylphosph...)
Affinity DataIC50: 7nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354331(3-((4-((4-(3-(3-(tert-Butyl)-1-(3-((dimethylphosph...)
Affinity DataIC50: 7nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM354273(1-(3-(tert-Butyl)-1-(4-(dimethylphosphoryl)phenyl)...)
Affinity DataIC50: 8nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354308(1-(3-(tert-Butyl)-1-(3-((diethylphosphoryl)methyl)...)
Affinity DataIC50: 8nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354323(1-(1-(3-((Dimethylphosphoryl)methyl)phenyl)-3-isop...)
Affinity DataIC50: 8nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM354332(1-(3-(tert-Butyl)-1-(3-((dimethylphosphoryl)methyl...)
Affinity DataIC50: 8nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354294(1-(3-(tert-Butyl)-1-(4-(diethylphosphoryl)phenyl)-...)
Affinity DataIC50: 9nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM354308(1-(3-(tert-Butyl)-1-(3-((diethylphosphoryl)methyl)...)
Affinity DataIC50: 9nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354329(1-(4-((2-((3-cyano-5-(2-morpholinoethoxy)phenyl)am...)
Affinity DataIC50: 9nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354309(1-(1-(3-((Dimethylphosphoryl)methyl)phenyl)-3-isop...)
Affinity DataIC50: 10nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM354310(3-((4-((4-(3-(1-(3-((Dimethylphosphoryl)methyl)phe...)
Affinity DataIC50: 10nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354276(1-(1-(4-(Dimethylphosphoryl)phenyl)-3-isopropyl-1H...)
Affinity DataIC50: 12nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM354330(3-((4-((4-(3-(3-(tert-Butyl)-1-(3-((dimethylphosph...)
Affinity DataIC50: 12nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM354311(1-(1-(3-((Dimethylphosphoryl)methyl)phenyl)-3-isop...)
Affinity DataIC50: 13nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354333(1-(3-(tert-Butyl)-1-(3-((dimethylphosphoryl)methyl...)
Affinity DataIC50: 14nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354273(1-(3-(tert-Butyl)-1-(4-(dimethylphosphoryl)phenyl)...)
Affinity DataIC50: 15nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandPNGBDBM354275(N-(4-((4-(3-(3-(tert-Butyl)-1-(4-(dimethylphosphor...)
Affinity DataIC50: 16nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3 enzyme isoform (Invitrogen), are evaluated by determining the level of acti...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM354324(1-(4-((2-((3-(2,5,8,11-Tetraoxatridecan-13-yloxy)-...)
Affinity DataIC50: 18nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM354331(3-((4-((4-(3-(3-(tert-Butyl)-1-(3-((dimethylphosph...)
Affinity DataIC50: 18nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM354317(1-(1-(3-((Dimethylphosphoryl)methyl)phenyl)-3-isop...)
Affinity DataIC50: 21nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM354329(1-(4-((2-((3-cyano-5-(2-morpholinoethoxy)phenyl)am...)
Affinity DataIC50: 21nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM354322(3-((4-((4-(3-(1-(3-((Dimethylphosphoryl)methyl)phe...)
Affinity DataIC50: 24nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM354333(1-(3-(tert-Butyl)-1-(3-((dimethylphosphoryl)methyl...)
Affinity DataIC50: 24nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM354302(1-(3-(tert-Butyl)-1-(4-(dimethylphosphoryl)phenyl)...)
Affinity DataIC50: 27nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM354273(1-(3-(tert-Butyl)-1-(4-(dimethylphosphoryl)phenyl)...)
Affinity DataIC50: 34nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354295(1-(3-(tert-Butyl)-1-(3-((dimethylphosphoryl)methyl...)
Affinity DataIC50: 40nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM354293(1-(3-(tert-Butyl)-1-(4-(dimethylphosphoryl)phenyl)...)
Affinity DataIC50: 44nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354314(1-(1-(3-((Dimethylphosphoryl)methyl)phenyl)-3-isop...)
Affinity DataIC50: 47nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM354287(1-(3-(tert-Butyl)-1-(4-(dimethylphosphoryl)phenyl)...)
Affinity DataIC50: 56nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandPNGBDBM354313(1-(3-(tert-Butyl)-1-(3-((dimethylphosphoryl)methyl...)
Affinity DataIC50: 56nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM354323(1-(1-(3-((Dimethylphosphoryl)methyl)phenyl)-3-isop...)
Affinity DataIC50: 58nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM354304(1-(3-(tert-Butyl)-1-(3-((dimethylphosphoryl)methyl...)
Affinity DataIC50: 60nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
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US Patent
LigandPNGBDBM354314(1-(1-(3-((Dimethylphosphoryl)methyl)phenyl)-3-isop...)
Affinity DataIC50: 63nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM354294(1-(3-(tert-Butyl)-1-(4-(diethylphosphoryl)phenyl)-...)
Affinity DataIC50: 67nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandPNGBDBM354292(1-(4-((2-((3-Aminobenzo[d]isoxazol-5-yl)amino)pyri...)
Affinity DataIC50: 68nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3 enzyme isoform (Invitrogen), are evaluated by determining the level of acti...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM354309(1-(1-(3-((Dimethylphosphoryl)methyl)phenyl)-3-isop...)
Affinity DataIC50: 70nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandPNGBDBM354332(1-(3-(tert-Butyl)-1-(3-((dimethylphosphoryl)methyl...)
Affinity DataIC50: 71nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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