Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 1831
TargetFibroblast growth factor receptor 2(Human)
Celon Pharma

US Patent
LigandPNGBDBM342461(US9776988, Example 21)
Affinity DataIC50: 0.950nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
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Date in BDB:
8/11/2019
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TargetFibroblast growth factor receptor 2(Human)
Celon Pharma

US Patent
LigandPNGBDBM342487(US9776988, Example 3)
Affinity DataIC50: 1.07nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
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Date in BDB:
8/11/2019
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TargetFibroblast growth factor receptor 2(Human)
Celon Pharma

US Patent
LigandPNGBDBM342463(US9776988, Example 27)
Affinity DataIC50: 1.26nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
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TargetFibroblast growth factor receptor 2(Human)
Celon Pharma

US Patent
LigandPNGBDBM342456(US9776988, Example 14)
Affinity DataIC50: 1.63nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
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TargetFibroblast growth factor receptor 2(Human)
Celon Pharma

US Patent
LigandPNGBDBM339992(US9776988, Example 18)
Affinity DataIC50: 2.05nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
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TargetFibroblast growth factor receptor 2(Human)
Celon Pharma

US Patent
LigandPNGBDBM340025(US9776988, Example 8)
Affinity DataIC50: 2.13nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
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TargetFibroblast growth factor receptor 2(Human)
Celon Pharma

US Patent
LigandPNGBDBM342472(US9776988, Example 4)
Affinity DataIC50: 2.18nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
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Date in BDB:
8/11/2019
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TargetFibroblast growth factor receptor 2(Human)
Celon Pharma

US Patent
LigandPNGBDBM340013(US9776988, Example 2)
Affinity DataIC50: 2.19nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
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TargetFibroblast growth factor receptor 1(Human)
Celon Pharma

US Patent
LigandPNGBDBM342461(US9776988, Example 21)
Affinity DataIC50: 3.52nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
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TargetFibroblast growth factor receptor 1(Human)
Celon Pharma

US Patent
LigandPNGBDBM339992(US9776988, Example 18)
Affinity DataIC50: 4.72nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
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TargetFibroblast growth factor receptor 1(Human)
Celon Pharma

US Patent
LigandPNGBDBM342463(US9776988, Example 27)
Affinity DataIC50: 6.54nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
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Date in BDB:
8/11/2019
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TargetFibroblast growth factor receptor 1(Human)
Celon Pharma

US Patent
LigandPNGBDBM340013(US9776988, Example 2)
Affinity DataIC50: 7.80nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Celon Pharma

US Patent
LigandPNGBDBM339992(US9776988, Example 18)
Affinity DataIC50: 8.65nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetFibroblast growth factor receptor 1(Human)
Celon Pharma

US Patent
LigandPNGBDBM340025(US9776988, Example 8)
Affinity DataIC50: 9.65nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Celon Pharma

US Patent
LigandPNGBDBM342461(US9776988, Example 21)
Affinity DataIC50: 10.5nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetFibroblast growth factor receptor 1(Human)
Celon Pharma

US Patent
LigandPNGBDBM342487(US9776988, Example 3)
Affinity DataIC50: 11.3nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetFibroblast growth factor receptor 1(Human)
Celon Pharma

US Patent
LigandPNGBDBM342472(US9776988, Example 4)
Affinity DataIC50: 11.3nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetFibroblast growth factor receptor 1(Human)
Celon Pharma

US Patent
LigandPNGBDBM342456(US9776988, Example 14)
Affinity DataIC50: 16nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Celon Pharma

US Patent
LigandPNGBDBM342463(US9776988, Example 27)
Affinity DataIC50: 17.8nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Celon Pharma

US Patent
LigandPNGBDBM340025(US9776988, Example 8)
Affinity DataIC50: 22.2nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
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TargetFibroblast growth factor receptor 3(Human)
Celon Pharma

US Patent
LigandPNGBDBM340013(US9776988, Example 2)
Affinity DataIC50: 25.3nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Celon Pharma

US Patent
LigandPNGBDBM342472(US9776988, Example 4)
Affinity DataIC50: 29.8nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Celon Pharma

US Patent
LigandPNGBDBM342456(US9776988, Example 14)
Affinity DataIC50: 33.1nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Celon Pharma

US Patent
LigandPNGBDBM342487(US9776988, Example 3)
Affinity DataIC50: 40.5nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Celon Pharma

US Patent
LigandPNGBDBM342461(US9776988, Example 21)
Affinity DataIC50: 44nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Celon Pharma

US Patent
LigandPNGBDBM342487(US9776988, Example 3)
Affinity DataIC50: 70.4nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Celon Pharma

US Patent
LigandPNGBDBM340025(US9776988, Example 8)
Affinity DataIC50: 79.3nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Celon Pharma

US Patent
LigandPNGBDBM339992(US9776988, Example 18)
Affinity DataIC50: 81.6nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Celon Pharma

US Patent
LigandPNGBDBM342472(US9776988, Example 4)
Affinity DataIC50: 82.9nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Celon Pharma

US Patent
LigandPNGBDBM342463(US9776988, Example 27)
Affinity DataIC50: 88.1nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Celon Pharma

US Patent
LigandPNGBDBM340013(US9776988, Example 2)
Affinity DataIC50: 114nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Celon Pharma

US Patent
LigandPNGBDBM342456(US9776988, Example 14)
Affinity DataIC50: 125nMAssay Description:The compounds were dissolved in 100% DMSO, and obtained solutions were serially diluted in reaction buffer (50 mM Tris pH 7.5, 10 mM MgCl2, 0.25 mM E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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