Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 1742
TargetMitogen-activated protein kinase 14(Human)
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LigandPNGBDBM337710(2-(2-(2-(4-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 8nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
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Date in BDB:
7/11/2019
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TargetTyrosine-protein kinase SYK(Human)
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LigandPNGBDBM337710(2-(2-(2-(4-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 8nMAssay Description:Method 1The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the...More data for this Ligand-Target Pair
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Date in BDB:
7/11/2019
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TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandPNGBDBM298395(US10125100, Example 17(a) | 4-[[4-[[4-[[5-tert-but...)
Affinity DataIC50: 16nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
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Date in BDB:
7/11/2019
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TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandPNGBDBM298427(US10125100, Example 17(ag) | 4-[[4-[[4-[[5-tert-bu...)
Affinity DataIC50: 17nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
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Date in BDB:
7/11/2019
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TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandPNGBDBM298428(US10125100, Example 17(ah) | 4-[[4-[[4-[[5-tert-bu...)
Affinity DataIC50: 20nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
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Date in BDB:
7/11/2019
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TargetProto-oncogene tyrosine-protein kinase Src(Human)
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LigandPNGBDBM337710(2-(2-(2-(4-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50: 22nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
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Date in BDB:
7/11/2019
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TargetTyrosine-protein kinase SYK(Human)
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LigandPNGBDBM298428(US10125100, Example 17(ah) | 4-[[4-[[4-[[5-tert-bu...)
Affinity DataIC50: 57nMAssay Description:Method 1The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the...More data for this Ligand-Target Pair
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Date in BDB:
7/11/2019
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TargetTyrosine-protein kinase SYK(Human)
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LigandPNGBDBM298427(US10125100, Example 17(ag) | 4-[[4-[[4-[[5-tert-bu...)
Affinity DataIC50: 105nMAssay Description:Method 1The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the...More data for this Ligand-Target Pair
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Date in BDB:
7/11/2019
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TargetGlycogen synthase kinase-3 alpha(Human)
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LigandPNGBDBM298427(US10125100, Example 17(ag) | 4-[[4-[[4-[[5-tert-bu...)
Affinity DataIC50: 2.75E+3nMMore data for this Ligand-Target Pair
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Date in BDB:
7/11/2019
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TargetGlycogen synthase kinase-3 alpha(Human)
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LigandPNGBDBM298395(US10125100, Example 17(a) | 4-[[4-[[4-[[5-tert-but...)
Affinity DataIC50: 4.00E+3nMMore data for this Ligand-Target Pair
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Date in BDB:
7/11/2019
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TargetGlycogen synthase kinase-3 alpha(Human)
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LigandPNGBDBM298428(US10125100, Example 17(ah) | 4-[[4-[[4-[[5-tert-bu...)
Affinity DataIC50: 9.19E+3nMMore data for this Ligand-Target Pair
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Date in BDB:
7/11/2019
Entry Details
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