Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 1735
TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM337629(6-Ethyl-4-hydroxypyridazin-3(2H)-one | US9750748, ...)
Affinity DataIC50: 11nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ...More data for this Ligand-Target Pair
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Date in BDB:
7/11/2019
Entry Details
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TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM337636(4-Hydroxy-6-isopropylpyridazin-3(2H)-one | US97507...)
Affinity DataIC50: 36nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ...More data for this Ligand-Target Pair
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Date in BDB:
7/11/2019
Entry Details
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TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM337631(6-Cyclopropyl-4-hydroxypyridazin-3(2H)-one | US975...)
Affinity DataIC50: 40nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM337644(6-tert-Butyl-4-hydroxypyridazin-3(2H)-one | US9750...)
Affinity DataIC50: 44nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM337638(6-(Dimethylamino)-4-hydroxypyridazin-3(2H)-one | U...)
Affinity DataIC50: 46nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ...More data for this Ligand-Target Pair
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Date in BDB:
7/11/2019
Entry Details
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TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM337630(4-Hydroxy-6-(3-methylbutyl)pyridazin-3(2H)-one | U...)
Affinity DataIC50: 61nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM337633(4-Hydroxy-6-(2-methylpropyl)pyridazin-3(2H)-one | ...)
Affinity DataIC50: 140nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM337642(6-(Ethyl(methyl)amino)-4-hydroxypyridazin-3(2H)-on...)
Affinity DataIC50: 150nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM337641(4-Hydroxy-6-(methyl(propyl)amino)pyridazin-3(2H)-o...)
Affinity DataIC50: 180nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM337634(6-Cyclopentyl-4-hydroxypyridazin-3(2H)-one | US975...)
Affinity DataIC50: 670nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ...More data for this Ligand-Target Pair
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Date in BDB:
7/11/2019
Entry Details
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TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM337635(6-Cyclohexyl-4-hydroxypyridazin-3(2H)-one | BDBM50...)
Affinity DataIC50: 1.10E+3nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ...More data for this Ligand-Target Pair
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Date in BDB:
7/11/2019
Entry Details
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TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM337637(6-(Azetidin-1-yl)-4-hydroxypyridazin-3(2H)-one | U...)
Affinity DataIC50: 2.50E+3nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM337643(4-Hydroxy-6-(piperidin-1-yl)pyridazin-3(2H)-one | ...)
Affinity DataIC50: 3.60E+3nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
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TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM337632(4-Hydroxy-6-(tetrahydro-2H-pyran-4-yl)pyridazin-3(...)
Affinity DataIC50: 4.10E+3nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2, which ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
Go to US Patent