Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 1703
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Basilea Pharmaceutica

US Patent
LigandPNGBDBM336125(US9738676, Comparative Compound A)
Affinity DataIC50: 0.100nMAssay Description:PDEs specifically hydrolyze cAMP and/or cGMP and release the product AMP and/or GMP. The potency of PDE inhibition by test compounds is determined wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Basilea Pharmaceutica

US Patent
LigandPNGBDBM336122(US9738676, WS2009/106419, Expl. 10)
Affinity DataIC50: 31nMAssay Description:PDEs specifically hydrolyze cAMP and/or cGMP and release the product AMP and/or GMP. The potency of PDE inhibition by test compounds is determined wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Basilea Pharmaceutica

US Patent
LigandPNGBDBM336127(US9738676, Compound of Formula (I-A) according to ...)
Affinity DataIC50: 35nMAssay Description:PDEs specifically hydrolyze cAMP and/or cGMP and release the product AMP and/or GMP. The potency of PDE inhibition by test compounds is determined wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Basilea Pharmaceutica

US Patent
LigandPNGBDBM336126(US9738676, Comparative Compound B)
Affinity DataIC50: 43nMAssay Description:PDEs specifically hydrolyze cAMP and/or cGMP and release the product AMP and/or GMP. The potency of PDE inhibition by test compounds is determined wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Basilea Pharmaceutica

US Patent
LigandPNGBDBM336123(US9738676, WS2009/106419, Expl. 15)
Affinity DataIC50: 71nMAssay Description:PDEs specifically hydrolyze cAMP and/or cGMP and release the product AMP and/or GMP. The potency of PDE inhibition by test compounds is determined wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Basilea Pharmaceutica

US Patent
LigandPNGBDBM336121(US9738676, WS2009/106419, Expl. 9)
Affinity DataIC50: 300nMAssay Description:PDEs specifically hydrolyze cAMP and/or cGMP and release the product AMP and/or GMP. The potency of PDE inhibition by test compounds is determined wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Basilea Pharmaceutica

US Patent
LigandPNGBDBM136699(US8865662, 3 | US9738676, WS2011/018510, Expl. 2)
Affinity DataIC50: 876nMAssay Description:PDEs specifically hydrolyze cAMP and/or cGMP and release the product AMP and/or GMP. The potency of PDE inhibition by test compounds is determined wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
Go to US Patent