Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 1631
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333401(2-{[3-(Furo[2,3-c]pyridin-2-yl)imidazo[1,2-b]pyrid...)
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
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TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333402(2-{[3-(Furo[3,2-c]pyridin-2-yl)imidazo[1,2-b]pyrid...)
Affinity DataIC50: 1nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
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TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333382(3-[(1R)-1-{[3-(1- Benzofuran-2- yl)imidazo[1,2-b]p...)
Affinity DataIC50: 2nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
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TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333390(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...)
Affinity DataIC50: 2nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
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TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333403(2-{[3-(4-Methoxyfuro[3,2-c]pyridin-2-yl)imidazo[1,...)
Affinity DataIC50: 3nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
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TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333389(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...)
Affinity DataIC50: 4nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
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TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333391((−)-2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]p...)
Affinity DataIC50: 4nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
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TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333388(3-[(1R)-1-Hydroxy-2- {[3-(4-methoxy-1- benzofuran-...)
Affinity DataIC50: 4nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
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TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333404(2-{[3-(4-Ethoxyfuro[3,2-c]pyridin-2-yl)imidazo[1,2...)
Affinity DataIC50: 5nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
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TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333384(2-{[3-(1- Benzofuran-2- yl)imidazo[1,2-b]pyridazi...)
Affinity DataIC50: 9nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
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TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333393(1-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...)
Affinity DataIC50: 9nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333394(1-{[3-(4-Methoxyfuro[3,2-c]pyridin-2-yl)imidazo[1,...)
Affinity DataIC50: 10nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM214649(US9284319, R7 | US9730929, Example R7 | US9783543,...)
Affinity DataIC50: 13nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333385(3-{[3-(1-Benzofuran-2- yl)imidazo[1,2-b]pyridazin-...)
Affinity DataIC50: 19nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333380(2-{[3-(1-Benzofuran-2-yl)imidazo[1, 2-b]pyridazin-...)
Affinity DataIC50: 20nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333381(N-(2-{[3-(1-Benzofuran-2- yl)imidazo[1,2-b]pyridaz...)
Affinity DataIC50: 21nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333392((+)-2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridaz...)
Affinity DataIC50: 24nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333395(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...)
Affinity DataIC50: 24nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333396(2-{[3-(4-Methoxyfuro[3,2-c]pyridin-2-yl)imidazo[1,...)
Affinity DataIC50: 26nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM214650(US9284319, R8 | US9730929, Example R8 | US9783543,...)
Affinity DataIC50: 34nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333397(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...)
Affinity DataIC50: 42nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333387(2-(1-{[3-(1- Benzofuran-2- yl)imidazo[1,2-b]pyrida...)
Affinity DataIC50: 45nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333398(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...)
Affinity DataIC50: 47nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333399(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...)
Affinity DataIC50: 48nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333400(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...)
Affinity DataIC50: 52nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333386(3-{[3-(1-Benzofuran-2- yl)imidazo[1,2-b]pyridazin-...)
Affinity DataIC50: 99nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM333383(4-{[3-(1- Benzofuran-2- yl)imidazo[1,2-b]pyridazin...)
Affinity DataIC50: 121nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM214644(US9284319, R2 | US9730929, Example R2 | US9783543,...)
Affinity DataIC50: 170nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM214645(US9284319, R2 | US9730929, Example R3 | US9783543,...)
Affinity DataIC50: 230nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM214648(US9284319, R6 | US9730929, Example R6 | US9783543,...)
Affinity DataIC50: 250nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM214643(US9284319, R1 | US9730929, Example R1 | US9783543,...)
Affinity DataIC50: 370nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM214647(US9284319, R5 | US9730929, Example R5 | US9783543,...)
Affinity DataIC50: 480nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM214646(US9284319, R4 | US9730929, Example R4 | US9783543,...)
Affinity DataIC50: 810nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2019
Entry Details
Go to US Patent