Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 374
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264170((E)-N-(7-(((R)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50: 1.20nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264162((R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-met...)
Affinity DataIC50: 1.40nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264168((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-((S)-tet...)
Affinity DataIC50: 1.5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264129((R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-methox...)
Affinity DataIC50: 1.60nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264129((R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-methox...)
Affinity DataIC50: 1.60nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264160((R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-ethoxy...)
Affinity DataIC50: 1.60nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264162((R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-met...)
Affinity DataIC50: 1.90nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264160((R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-ethoxy...)
Affinity DataIC50: 2nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264128((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-methoxyq...)
Affinity DataIC50: 2.30nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264169((E)-N-(7-(((R)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50: 2.70nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264175((E)-N-(7-((1R,5S,6R)-3-oxabicyclo[3.1.0]hexan-6-yl...)
Affinity DataIC50: 2.80nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264175((E)-N-(7-((1R,5S,6R)-3-oxabicyclo[3.1.0]hexan-6-yl...)
Affinity DataIC50: 2.90nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264168((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-((S)-tet...)
Affinity DataIC50: 2.90nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264170((E)-N-(7-(((R)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50: 2.90nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264167((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-((S)-tet...)
Affinity DataIC50: 3.90nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264163((S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-met...)
Affinity DataIC50: 4.60nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264173((E)-N-(7-(((S)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50: 4.80nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264173((E)-N-(7-(((S)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50: 5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264128((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-methoxyq...)
Affinity DataIC50: 5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264163((S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-met...)
Affinity DataIC50: 5.80nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264165((R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(cyclo...)
Affinity DataIC50: 6.60nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264161((S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-ethoxy...)
Affinity DataIC50: 7.80nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264161((S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-ethoxy...)
Affinity DataIC50: 8.10nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264164((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(cyclopr...)
Affinity DataIC50: 9.5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264167((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-((S)-tet...)
Affinity DataIC50: 9.60nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264174((E)-N-(7-((1R,5S,6R)-3-oxabicyclo[3.1.0]hexan-6-yl...)
Affinity DataIC50: 10.8nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264174((E)-N-(7-((1R,5S,6R)-3-oxabicyclo[3.1.0]hexan-6-yl...)
Affinity DataIC50: 11.2nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264171((E)-N-(7-(((R)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50: 11.2nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264164((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(cyclopr...)
Affinity DataIC50: 11.8nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264169((E)-N-(7-(((R)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50: 13.5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264159((S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-methox...)
Affinity DataIC50: 14.2nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264165((R,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(cyclo...)
Affinity DataIC50: 15.5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264176((E)-N-(7-((1R,5S,6R)-3-oxabicyclo[3.1.0]hexan-6-yl...)
Affinity DataIC50: 15.6nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264172((E)-N-(7-(((S)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50: 17.5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264159((S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-methox...)
Affinity DataIC50: 21.5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264166((S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(cyclo...)
Affinity DataIC50: 21.7nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264176((E)-N-(7-((1R,5S,6R)-3-oxabicyclo[3.1.0]hexan-6-yl...)
Affinity DataIC50: 22.2nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264171((E)-N-(7-(((R)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50: 25nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264166((S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(cyclo...)
Affinity DataIC50: 32.8nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM264172((E)-N-(7-(((S)-1,4-dioxan-2-yl)methoxy)-4-(3-chlor...)
Affinity DataIC50: 39.5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
In DepthDetails
US Patent