Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 272
TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM261619(US9708275, Compound 16 | (S)-4-(1-benzyl-3-methyl-...)
Affinity DataIC50: 40.3nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM261620(US9708275, Compound 23 | (S)-4-(1-benzyl-3-(-trifl...)
Affinity DataIC50: 93.8nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM261615((S)-1-(2,2-diphenylacetyl)-4-(3-methyl-1-phenyl-1H...)
Affinity DataIC50: 155nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM261613(US9708275, Compound 5 | (S)-4-benzyl-1-(2,2-diphen...)
Affinity DataIC50: 383nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM261612(US9708275, Compound 4 | (S)-1-(2,2-diphenylacetyl...)
Affinity DataIC50: 408nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM261615((S)-1-(2,2-diphenylacetyl)-4-(3-methyl-1-phenyl-1H...)
Affinity DataIC50: 517nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM261616(US9708275, Compound 8 | (S)-1-(2,2-diphenylacetyl)...)
Affinity DataIC50: 1.27E+3nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM261623(US9708275, Compound 26 | (S)-1-(2,2-diphenylacetyl...)
Affinity DataIC50: 1.32E+3nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM261614(US9708275, Compound 6 | S)-4-(1,5-diphenyl-1H-pyra...)
Affinity DataIC50: 3.05E+3nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM261622(US9708275, Compound 25 | (S)-1-(2,2-diphenylacetyl...)
Affinity DataIC50: 3.92E+3nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM261617(US9708275, Compound 9 | (S)-4-cinnamyl-1-(2,2-diph...)
Affinity DataIC50: 4.11E+3nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetType-2 angiotensin II receptor(Human)
Novartis

US Patent
LigandPNGBDBM261621(US9708275, Compound 24 | (S)-1-(2,2-diphenylacetyl...)
Affinity DataIC50: 4.16E+3nMAssay Description:120 μL membrane (5 mg protein/well) was incubated with 15 μL of [125I]-CGP42112A and 15 μL of compound at RT for 1.5 hrs.The binding r...More data for this Ligand-Target Pair
In DepthDetails
US Patent