Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 253
TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM255774(US9701693, 4 | (3aR,5R,6S,7S,7aR)-5- (hydroxymethy...)
Affinity DataKi:  0.700nM ΔG°:  -52.3kJ/moleT: 2°CAssay Description:A variety of tissue culture cell lines, expressing endogenous levels of O-GlcNAcase, can be utilized; examples include rat PC-12, and human U-87, or ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM255773(US9701693, 3 | (3aR,5R,6S,7S,7aR)-2-(ethylamino)- ...)
Affinity DataKi:  7.30nM ΔG°:  -46.4kJ/moleT: 2°CAssay Description:A variety of tissue culture cell lines, expressing endogenous levels of O-GlcNAcase, can be utilized; examples include rat PC-12, and human U-87, or ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM255772(US9701693, 2 | (3aR,5R,6R,7R,7aR)-2- (dimethylamin...)
Affinity DataKi:  28.6nM ΔG°:  -43.1kJ/moleT: 2°CAssay Description:A variety of tissue culture cell lines, expressing endogenous levels of O-GlcNAcase, can be utilized; examples include rat PC-12, and human U-87, or ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM255771(US9701693, 1 | (3aR,5R,6R,7R,7aR)-5- (hydroxymethy...)
Affinity DataKi:  243nM ΔG°:  -37.8kJ/moleT: 2°CAssay Description:A variety of tissue culture cell lines, expressing endogenous levels of O-GlcNAcase, can be utilized; examples include rat PC-12, and human U-87, or ...More data for this Ligand-Target Pair
In DepthDetails
US Patent