Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 86
TargetRho-associated protein kinase 2(Rat)
Bioaxone Biosciences

US Patent
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 820nMT: 2°CAssay Description:The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetRho-associated protein kinase 2(Rat)
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(US9687483, 1 | BA-1049 | US11198680, Compound BA 1...)
Affinity DataIC50: 940nMT: 2°CAssay Description:The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRho-associated protein kinase 2(Rat)
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(US9687483, 1 | BA-1049 | US11198680, Compound BA 1...)
Affinity DataIC50: 1.60E+3nMT: 2°CAssay Description:The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetRho-associated protein kinase 1(Rat)
Bioaxone Biosciences

US Patent
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 2.10E+3nMT: 2°CAssay Description:The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetRho-associated protein kinase 1(Rat)
Bioaxone Biosciences

US Patent
LigandPNGBDBM163433(US9687483, 1 | BA-1049 | US11198680, Compound BA 1...)
Affinity DataIC50: 2.10E+4nMT: 2°CAssay Description:The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...More data for this Ligand-Target Pair
In DepthDetails
US Patent