Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 1079
TargetBeta-secretase 1 [1-460](Human)
Astrazeneca

US Patent
LigandPNGBDBM50005021(CHEMBL2408786 | US9650336, Example 3)
Affinity DataIC50: 18nMAssay Description:The cDNA for the soluble part of the human 13-Secretase (AA 1-AA 460) was cloned using the ASP2-Fc10-1-IRES-GFP-neoK mammalian expression vector. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1 [1-460](Human)
Astrazeneca

US Patent
LigandPNGBDBM50005022(CHEMBL2408787 | US9650336, Example 1)
Affinity DataIC50: 22nMAssay Description:The cDNA for the soluble part of the human 13-Secretase (AA 1-AA 460) was cloned using the ASP2-Fc10-1-IRES-GFP-neoK mammalian expression vector. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1 [1-460](Human)
Astrazeneca

US Patent
LigandPNGBDBM307707(US9650336, Example 10 | 4''-fluoro-6'-(3-fluoropro...)
Affinity DataIC50: 37nMAssay Description:The cDNA for the soluble part of the human 13-Secretase (AA 1-AA 460) was cloned using the ASP2-Fc10-1-IRES-GFP-neoK mammalian expression vector. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1 [1-460](Human)
Astrazeneca

US Patent
LigandPNGBDBM307702(US9650336, Example 5)
Affinity DataIC50: 71nMAssay Description:The cDNA for the soluble part of the human 13-Secretase (AA 1-AA 460) was cloned using the ASP2-Fc10-1-IRES-GFP-neoK mammalian expression vector. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1 [1-460](Human)
Astrazeneca

US Patent
LigandPNGBDBM50005019(CHEMBL2408785 | US9650336, Example 4)
Affinity DataIC50: 258nMAssay Description:The cDNA for the soluble part of the human 13-Secretase (AA 1-AA 460) was cloned using the ASP2-Fc10-1-IRES-GFP-neoK mammalian expression vector. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1 [1-460](Human)
Astrazeneca

US Patent
LigandPNGBDBM307705(US9650336, Example 8)
Affinity DataIC50: 640nMAssay Description:The cDNA for the soluble part of the human 13-Secretase (AA 1-AA 460) was cloned using the ASP2-Fc10-1-IRES-GFP-neoK mammalian expression vector. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1 [1-460](Human)
Astrazeneca

US Patent
LigandPNGBDBM307703(US9650336, Example 6)
Affinity DataIC50: 770nMAssay Description:The cDNA for the soluble part of the human 13-Secretase (AA 1-AA 460) was cloned using the ASP2-Fc10-1-IRES-GFP-neoK mammalian expression vector. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1 [1-460](Human)
Astrazeneca

US Patent
LigandPNGBDBM307704(US9650336, Example 7)
Affinity DataIC50: 770nMAssay Description:The cDNA for the soluble part of the human 13-Secretase (AA 1-AA 460) was cloned using the ASP2-Fc10-1-IRES-GFP-neoK mammalian expression vector. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1 [1-460](Human)
Astrazeneca

US Patent
LigandPNGBDBM307708(US9650336, Example 11 | 4''-fluoro-6'-(3-fluoropro...)
Affinity DataIC50: 1.22E+3nMAssay Description:The cDNA for the soluble part of the human 13-Secretase (AA 1-AA 460) was cloned using the ASP2-Fc10-1-IRES-GFP-neoK mammalian expression vector. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1 [1-460](Human)
Astrazeneca

US Patent
LigandPNGBDBM307699(US9650336, Example 2)
Affinity DataIC50: 1.97E+3nMAssay Description:The cDNA for the soluble part of the human 13-Secretase (AA 1-AA 460) was cloned using the ASP2-Fc10-1-IRES-GFP-neoK mammalian expression vector. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 1 [1-460](Human)
Astrazeneca

US Patent
LigandPNGBDBM50005020(CHEMBL2408784 | US9650336, Example 9)
Affinity DataIC50: 3.79E+3nMAssay Description:The cDNA for the soluble part of the human 13-Secretase (AA 1-AA 460) was cloned using the ASP2-Fc10-1-IRES-GFP-neoK mammalian expression vector. The...More data for this Ligand-Target Pair
In DepthDetails
US Patent