Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 1355
LigandPNGBDBM317637(US9624205, 6)
Affinity DataIC50: 233nMMore data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM317634(US9624205, 3)
Affinity DataIC50: 548nMMore data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
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LigandPNGBDBM317635(US9624205, 4)
Affinity DataIC50: 1.10E+3nMMore data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM317637(US9624205, 6)
Affinity DataIC50: 1.47E+3nMAssay Description:The assays were performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG, 100 mM KCl and 0.002% Tween20, prepared on the day...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
Entry Details
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LigandPNGBDBM317636(US9624205, 5)
Affinity DataIC50: 1.99E+3nMMore data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM317634(US9624205, 3)
Affinity DataIC50: 4.33E+3nMAssay Description:The assays were performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG, 100 mM KCl and 0.002% Tween20, prepared on the day...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM317635(US9624205, 4)
Affinity DataIC50: 5.63E+3nMAssay Description:The assays were performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG, 100 mM KCl and 0.002% Tween20, prepared on the day...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM317636(US9624205, 5)
Affinity DataIC50: 2.20E+4nMAssay Description:The assays were performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG, 100 mM KCl and 0.002% Tween20, prepared on the day...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
Entry Details
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LigandPNGBDBM317632(US9624205, 1 | Syntheses of Compounds in Table 1A)
Affinity DataIC50: 2.80E+4nMMore data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM317632(US9624205, 1 | Syntheses of Compounds in Table 1A)
Affinity DataIC50: 5.00E+4nMAssay Description:The assays were performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG, 100 mM KCl and 0.002% Tween20, prepared on the day...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM317633(US9624205, 2 | 6-(aminomethyl)-5-(2-(dimethylamino...)
Affinity DataIC50: 5.00E+4nMAssay Description:The assays were performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG, 100 mM KCl and 0.002% Tween20, prepared on the day...More data for this Ligand-Target Pair
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Date in BDB:
5/15/2019
Entry Details
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LigandPNGBDBM317633(US9624205, 2 | 6-(aminomethyl)-5-(2-(dimethylamino...)
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent