Compile Data Set for Download or QSAR
Report error Found 67 Enz. Inhib. hit(s) with all data for entry = 1333
TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317482(US9623028, Compound 349 | 4-(4-((1s,4s)-4-hydroxy-...)
Affinity DataIC50: 1.15nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317480(US9623028, Compound 334 | 4-(4-isopropoxy-5-(4- (m...)
Affinity DataIC50: 1.42nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317482(US9623028, Compound 349 | 4-(4-((1s,4s)-4-hydroxy-...)
Affinity DataIC50: 1.43nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317475(US9623028, Compound 171 | 3-cyano-N-methyl-4-(5-(2...)
Affinity DataIC50: 1.47nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317466(US9623028, Compound 89 | 4-(4-methoxy-5-(pyridin-4...)
Affinity DataIC50: 1.5nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317467(US9623028, Compound 90 | 3-methoxy-N-methyl-4-(5-(...)
Affinity DataIC50: 1.68nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317471(US9623028, Compound 134 | (S)-3-chloro-N-methyl-4-...)
Affinity DataIC50: 1.68nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317485(US9623028, Compound 423 | 3-chloro-N-methyl-4-(5-(...)
Affinity DataIC50: 1.90nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317465(US9623028, Compound 79 | 4-(4-(cyclopentyloxy)-5-(...)
Affinity DataIC50: 1.91nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317483(US9623028, Compound 421 | 3-chloro-N-methyl-4-(5-(...)
Affinity DataIC50: 2.10nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317473(US9623028, Compound 146 | 4-(5-(4-(1H-imidazol-2- ...)
Affinity DataIC50: 2.12nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317468(US9623028, Compound 101 | 4-(4-(cyclopentyloxy)-5-...)
Affinity DataIC50: 2.13nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317471(US9623028, Compound 134 | (S)-3-chloro-N-methyl-4-...)
Affinity DataIC50: 2.27nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317469(US9623028, Compound 118 | 3-methoxy-4-(4-methoxy-5...)
Affinity DataIC50: 2.29nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317475(US9623028, Compound 171 | 3-cyano-N-methyl-4-(5-(2...)
Affinity DataIC50: 2.32nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317479(US9623028, Compound 304 | 4-(4-cyclobutoxy-5-(4- (...)
Affinity DataIC50: 2.35nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317465(US9623028, Compound 79 | 4-(4-(cyclopentyloxy)-5-(...)
Affinity DataIC50: 2.38nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317472(US9623028, Compound 145 | N,3-dimethyl-4-(5-(2- me...)
Affinity DataIC50: 2.45nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317474(US9623028, Compound 152 | 4-(4-cyclopropoxy-5-(2- ...)
Affinity DataIC50: 2.96nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317485(US9623028, Compound 423 | 3-chloro-N-methyl-4-(5-(...)
Affinity DataIC50: 3.29nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317468(US9623028, Compound 101 | 4-(4-(cyclopentyloxy)-5-...)
Affinity DataIC50: 3.38nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317467(US9623028, Compound 90 | 3-methoxy-N-methyl-4-(5-(...)
Affinity DataIC50: 3.5nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317476(US9623028, Compound 191 | N-methyl-4-(5-(2- methyl...)
Affinity DataIC50: 3.65nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317470(US9623028, Compound 132 | 3-chloro-N-methyl-4-(5-(...)
Affinity DataIC50: 4.12nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317460(US9623028, Compound 17 | 4-(5-(4-hydroxyphenyl)-4-...)
Affinity DataIC50: 4.33nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317478(US9623028, Compound 300 | 4-(4-(cyclopentyloxy)-5-...)
Affinity DataIC50: 4.54nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317466(US9623028, Compound 89 | 4-(4-methoxy-5-(pyridin-4...)
Affinity DataIC50: 4.56nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317469(US9623028, Compound 118 | 3-methoxy-4-(4-methoxy-5...)
Affinity DataIC50: 5.14nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317481(US9623028, Compound 339 | 4-(4-cyclobutoxy-5-(2- m...)
Affinity DataIC50: 5.92nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317481(US9623028, Compound 339 | 4-(4-cyclobutoxy-5-(2- m...)
Affinity DataIC50: 7nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317477(US9623028, Compound 237 | 4-(4-(cyclopentyloxy)-5-...)
Affinity DataIC50: 8.06nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317462(US9623028, Compound 38 | 4-(4-(cyclopentyloxy)-5-(...)
Affinity DataIC50: 8.17nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317476(US9623028, Compound 191 | N-methyl-4-(5-(2- methyl...)
Affinity DataIC50: 9.41nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317477(US9623028, Compound 237 | 4-(4-(cyclopentyloxy)-5-...)
Affinity DataIC50: 10.4nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317484(US9623028, Compound 422 | 3-chloro-4-(4-(cyclopent...)
Affinity DataIC50: 11.6nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317484(US9623028, Compound 422 | 3-chloro-4-(4-(cyclopent...)
Affinity DataIC50: 12.5nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317463(US9623028, Compound 55 | 4-(4-(cyclopentyloxy)-5-(...)
Affinity DataIC50: 13.3nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317462(US9623028, Compound 38 | 4-(4-(cyclopentyloxy)-5-(...)
Affinity DataIC50: 14nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase TTK(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317464(US9623028, Compound 67 | 4-(4-(cyclopentyloxy)-5-(...)
Affinity DataIC50: 16nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317458(US9623028, Compound 16 | 4-(4-(cyclopentylamino)-5...)
Affinity DataIC50: 26nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317470(US9623028, Compound 132 | 3-chloro-N-methyl-4-(5-(...)
Affinity DataIC50: 29.1nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317465(US9623028, Compound 79 | 4-(4-(cyclopentyloxy)-5-(...)
Affinity DataIC50: 34nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317456(US9623028, Compound 11 | 4-(4-(cyclopentyloxy)-5-(...)
Affinity DataIC50: 34.9nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317472(US9623028, Compound 145 | N,3-dimethyl-4-(5-(2- me...)
Affinity DataIC50: 40.1nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK1(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317466(US9623028, Compound 89 | 4-(4-methoxy-5-(pyridin-4...)
Affinity DataIC50: 41.5nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK2(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317455(US9623028, Compound 3 | 4-(4-(cyclopentyloxy)-5-(4...)
Affinity DataIC50: 53.9nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK1(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317465(US9623028, Compound 79 | 4-(4-(cyclopentyloxy)-5-(...)
Affinity DataIC50: 58.6nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK1(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317482(US9623028, Compound 349 | 4-(4-((1s,4s)-4-hydroxy-...)
Affinity DataIC50: 59.3nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK1(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317460(US9623028, Compound 17 | 4-(5-(4-hydroxyphenyl)-4-...)
Affinity DataIC50: 82.4nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetDual specificity protein kinase CLK1(Human)
Signal Pharmaceuticals

US Patent
LigandPNGBDBM317475(US9623028, Compound 171 | 3-cyano-N-methyl-4-(5-(2...)
Affinity DataIC50: 82.8nMAssay Description:The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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