Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 864
LigandPNGBDBM294481(US9586970, 2 | 1-(2-(2-(5,8-dimethyl-[1,2,4]triazo...)
Affinity DataIC50: 1.30nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294506(US9586970, 27 | N,3-Dimethyl-6-{2-[4-(2-oxopyrroli...)
Affinity DataIC50: 2.90nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294502(US9586970, 23 | 1-(2-{2-[3-Methyl-2-(trifluorometh...)
Affinity DataIC50: 3.10nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294496(US9586970, 17 | 1-[2-[2-(5,8-dimethyl-[1,2,4]triaz...)
Affinity DataIC50: 3.20nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294488(US9586970, 9 | 1-(2-((4, 8-dimethylquinazolin-2-yl...)
Affinity DataIC50: 4.60nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294482(US9586970, 3 | 1-[2-[E)-2-(5,8-dimethyl-[1,2,4]tri...)
Affinity DataIC50: 9.5nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294495(US9586970, 16 | 1-[1-(Cyclopropylmethyl)-2-(2-{5,8...)
Affinity DataIC50: 14.8nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294491(US9586970, 12 | 1-[1-(Cyclopropylmethyl)-2-(2-{4,7...)
Affinity DataIC50: 16.9nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294490(US9586970, 11 | 1-[2-(2-{4,7-Dimethyl-[1,2,4]triaz...)
Affinity DataIC50: 18nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294499(US9586970, 20 | 1-{2-[(E)-2-{4,7-Dimethyl-[1,2,4]t...)
Affinity DataIC50: 19.4nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294504(US9586970, 25 | 1-(2-{2-[3-methyl-2-(trifluorometh...)
Affinity DataIC50: 21.9nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294498(US9586970, 19 | 1-[1-(2,2-difluoroethyl)-2-(2-{5,8...)
Affinity DataIC50: 26.8nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294486(US9586970, 7 | 1-{1-Cyclopropyl-2-[2-(5,8-dimethyl...)
Affinity DataIC50: 27nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294494(US9586970, 15 | 1-[2-(2-{4,7-Dimethyl-[1,2,4]triaz...)
Affinity DataIC50: 29nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294492(US9586970, 13 | 1-[2-(2-{4,7-Dimethyl-[1,2,4]triaz...)
Affinity DataIC50: 36.7nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294478(US9586970, 1 | 1-(2-(2-(5,8-dimethyl-[1,2,4]triazo...)
Affinity DataIC50: 39nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent
PDB3D3D Structure (crystal)
LigandPNGBDBM294493(US9586970, 14 | 1-[1-(2,2-difluoroethyl)-2-(2-{4,7...)
Affinity DataIC50: 46.9nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294489(US9586970, 10 | 1-{2-[(E)-2-{4,7-dimethyl-[1,2,4]t...)
Affinity DataIC50: 54.6nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294503(US9586970, 24 | 1-(1-Methyl-2-{2-[3-methyl-2-(trif...)
Affinity DataIC50: 75.5nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294485(US9586970, 6 | 1-[1-cyclopropyl-2-[(E)-2-(5,8-dime...)
Affinity DataIC50: 81nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294505(US9586970, 26 | N,3-Dimethyl-6-{2-[1-methyl-4-(2-o...)
Affinity DataIC50: 112nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294501(US9586970, 22 | 1-[2-(2-{5,7-dimethyl-[1,2,4]triaz...)
Affinity DataIC50: 117nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM294483(US9586970, 4 | 1-(1-(Cyclopropylmethyl)-2-(2-(5, 8...)
Affinity DataIC50: 150nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM294487(US9586970, 8 | 2′-[(E)-2-(5,8-Dimethyl-[1,2,...)
Affinity DataIC50: 162nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM294497(US9586970, 18 | 1-[2-(2-{5,8-dimethyl-[1,2,4]triaz...)
Affinity DataIC50: 168nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM294500(US9586970, 21 | 1-[2-(2-{5,7-dimethyl-[1,2,4]triaz...)
Affinity DataIC50: 176nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM294484(US9586970, 5 | 1-(2-(2-(5,8-dimethyl-[1,2,4]triazo...)
Affinity DataIC50: 195nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
In DepthDetails
US Patent