Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 188
LigandPNGBDBM205030(process for preparing 2-(2-{2-[1-(2-fluorophenyl)-...)
Affinity DataIC50: 16nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205069(process for preparing 5-{2-[2-(fluoromethyl)phenyl...)
Affinity DataIC50: 17nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205019(process for preparing 1-(2-fluorophenyl)-5-{2-[2-(...)
Affinity DataIC50: 30nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205016(process for preparing 5-[2-(2-ethoxyphenyl)phenyl]...)
Affinity DataIC50: 37nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205066(process for preparing (e)-n-[(2-{2-[1-(2-fluorophe...)
Affinity DataIC50: 57nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205065(process for preparing 1-(2-fluorophenyl)-5-{2-[2-(...)
Affinity DataIC50: 58nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205077(process for preparing 2-{5-[2-(2-methoxyphenyl)phe...)
Affinity DataIC50: 64nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205079(process for preparing 1-[2-(difluoromethoxy)phenyl...)
Affinity DataIC50: 69nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205050(process for preparing 1-(2-fluorophenyl)-5-[2-(2-m...)
Affinity DataIC50: 110nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205067(process for preparing 2-{2-[1-(2-fluorophenyl)-1h-...)
Affinity DataIC50: 110nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205053(process for preparing 1-(2-fluorophenyl)-5-{2-[2-(...)
Affinity DataIC50: 190nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205080(process for preparing 2-(5-{2-[2-(difluoromethoxy)...)
Affinity DataIC50: 210nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205056(process for preparing 5-[2-(2-ethylphenyl)phenyl]-...)
Affinity DataIC50: 290nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205022(US9556132, 40 | US9556132, 5)
Affinity DataIC50: 290nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205049(process for preparing 5-{2-[2-(fluoromethoxy)pheny...)
Affinity DataIC50: 300nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205060(process for preparing 5-[2-(2-chlorophenyl)phenyl]...)
Affinity DataIC50: 360nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205051(process for preparing 1-(2-fluorophenyl)-5-{2-[2-(...)
Affinity DataIC50: 460nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205055(process for preparing 1-(2-fluorophenyl)-5-[2-(2-m...)
Affinity DataIC50: 510nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205073(process for preparing 1-(2-chlorophenyl)-5-[2-(2-m...)
Affinity DataIC50: 540nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205057(process for preparing 2-{2-[1-(2-fluorophenyl)-1h-...)
Affinity DataIC50: 550nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205059(process for preparing 5-[2-(2-bromophenyl)phenyl]-...)
Affinity DataIC50: 550nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205044(process for preparing methyl 2-(2-{2-[1-(2-fluorop...)
Affinity DataIC50: 590nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205071(process for preparing 2-{2-[1-(2-fluorophenyl)-1h-...)
Affinity DataIC50: 680nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205060(process for preparing 5-[2-(2-chlorophenyl)phenyl]...)
Affinity DataIC50: 700nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205028(process for preparing 5-{2-[2-(cyclopropylmethoxy)...)
Affinity DataIC50: 710nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205064(process for preparing (2-{2-[1-(2-fluorophenyl)-1h...)
Affinity DataIC50: 770nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205045(process for preparing 1-(2-fluorophenyl)-5-{2-[2-(...)
Affinity DataIC50: 770nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205076(process for preparing 5-[2-(2-fluorophenyl)phenyl]...)
Affinity DataIC50: 780nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205022(US9556132, 40 | US9556132, 5)
Affinity DataIC50: 800nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205062(process for preparing 2-{2-[1-(2-fluorophenyl)-1h-...)
Affinity DataIC50: 820nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205068(process for preparing 5-{2-[2-(difluoromethyl)phen...)
Affinity DataIC50: 870nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205081(process for preparing 1-phenyl-5-(2-phenylphenyl)-...)
Affinity DataIC50: 890nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205063(process for preparing 2-{2-[1-(2-fluorophenyl)-1h-...)
Affinity DataIC50: 900nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205054(process for preparing 2-(2-{2-[1-(2-fluorophenyl)-...)
Affinity DataIC50: 1.00E+3nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205072(process for preparing 1-(2-chlorophenyl)-5-[2-(2-f...)
Affinity DataIC50: 1.00E+3nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205078(process for preparing 1-[2-(difluoromethoxy)phenyl...)
Affinity DataIC50: 1.10E+3nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205074(process for preparing 1-(2-methoxyphenyl)-5-[2-(2-...)
Affinity DataIC50: 1.20E+3nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205075(process for preparing 2-{5-[2-(2-methoxyphenyl)phe...)
Affinity DataIC50: 1.20E+3nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205052(process for preparing 1-(2-fluorophenyl)-5-{2-[2-(...)
Affinity DataIC50: 1.70E+3nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205058(process for preparing 1-(2-fluorophenyl)-5-{2-[2-(...)
Affinity DataIC50: 1.70E+3nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM205004(process for preparing 2-{2-[1-(2-fluorophenyl)-1h-...)
Affinity DataIC50: 5.90E+3nMpH: 7.3Assay Description:Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...More data for this Ligand-Target Pair
In DepthDetails
US Patent